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The Alkaline phosphatase (ALP) is considered to be an enzyme that is naturally present throughout the body. It is seen in many variations in form of the isoenzymes. Each isoenzyme of the ALP is considered to be different, depending on where in the body it’s being produced
The bones make the isoenzyme also called as the ALP-2. The Levels of this enzyme would increase when the bones are said to be growing or the bone cells are active.
An ALP bone isoenzyme test would detect the abnormal levels of bone growth that might be associated with different diseases such as:
The doctor might order an ALP-2 test if the healthcare professional is concerned in case of a bone disease.
The ALP-2 test would monitor the bone disease treatment.
The higher levels of Isoenzyme test indicate the following:
The lower levels of Isoenzyme test indicate the following:
Here are some guidelines an individual can refer to once they have decided to undergo Alkaline Phosphatase Bone isoenzymes
The required documents needed for this test includes your valid government ID and an appropriate Doctor’s prescription.
There is no specific or special precaution that must be taken post this test.
However, if the result of this test is positive, then further tests may be needed to rule out further conditions. This would be required to determine the type of bone disease the patient is suffering from.
ALP bone isoenzymes normal range for the healthy adults would be 12.1 to 42.7.
The cost of ALP Isoenzymes in Delhi varies by region and facility. So, constantly get tested at trustworthy diagnostic centers like Ganesh Diagnostic. It is staffed by trained and experienced professionals to assure patient and visitor safety.
The average price for this Test is seen to differ from one center to another. The price is said to be between Rs 5000 to Rs. 8000 in Delhi.
Test Type | Alkaline Phosphatase (ALP) Bone Isoenzymes |
Includes | |
Preparation | |
Reporting | Within 24 hours* |
Test Price |
₹ 2600
|
This test is generally used to diagnose or even monitor the following conditions:
Isoenzymes of the ALP or alkaline phosphatase, it gets separated by the electrophoresis technique on the cellulose acetate, and these were also developed by the gel imprint which is a substrate. The gel was prepared in the alkaline buffer and also contained in β-naphthyl acid phosphate, which will be hydrolyzed to β-naphthyl and also phosphorus.
The isoenzymes present for ALP are: Four Isozymes
The Alkaline phosphatase is seen to be divided into four isozymes depending upon site of the tissue expression which are as follows : Intestinal ALP, Placental ALP, Germ cell ALP and then tissue nonspecific alkaline phosphatase or with liver or bone or kidney (L/B/K) ALP.
The Bone alkaline phosphatase (ALP) is considered to be an ectoenzyme which is attached to the outer surface of cell membrane of the osteoblasts by the compound - glycosylphosphatidylinositol.
It will be partly released into the bloodstream. The Bone ALP and the liver ALP constitutes for about 95% of the total ALP activity in the human serum.
Early check ups are always better than delayed ones. Safety, precaution & care is depicted from the several health checkups. Here, we present simple & comprehensive health packages for any kind of testing to ensure the early prescribed treatment to safeguard your health.