Allergy Screening (Tryptase) Test Cost & Procedure

Tryptase testing, for instance, might be beneficial: To establish if a recent case of anaphylaxis or anaphylactic shock, a severe allergic reaction, has happened.

To identify mast cell diseases, which are rare problems where either the body's mast cells are overactive or reactive in an unusual way; to follow patients with these disorders to determine whether their condition is improving or worsening.

Describe tryptase

An enzyme called tryptase is primarily present in mast cells. Mast cells, white blood cells and an immune system component are activated due to allergic reactions. Doctors can tell if a significant allergic reaction has occurred by doing a tryptase test. Also, it could be utilised to spot specific blood conditions that might impair the normal development or operation of mast cells.

What is measured by the test?

Mast cells store tryptase, a particular class of protein known as an enzyme. White blood cells, called mast cells, play a role in normal immune responses triggered during allergic reactions. There are mast cells all across the body. The locations where your body encounters external surroundings and objects—such as your skin, the surfaces of your airwaysand, character characteristics of the digestive system—are most prevalent. These areas have mast cells that can react fast to protect your body from poisons and invading invaders. Tryptase and histamine are among the substances that are swiftly released by mast cells when they are triggered. Many of the symptoms of allergies, such as flushing, itching, and breathing difficulties, are brought on by these substances.

Preparation:

• Tryptase levels in the blood often rise abruptly during a severe allergic reaction before returning to normal after 12 to 24 hours.
• Tryptase's precise function in the body is not fully understood.
• Yet, unexpectedly high blood tryptase levels indicate that mast cells have a role in medical events like life-threatening allergic responses.
• Tryptase measures mast cell activity because of its link to mast cell activation.

When should I get tested for tryptase?

Doctors most frequently order tryptase testing to confirm a diagnosis of anaphylaxis, a severe allergic reaction or to identify or track a blood issue like a mast cell disorder.

Procedure:

• Two tablespoons or about 1 ml of blood will be taken from you for the sample.
• This test must be performed at a diagnostic lab with a well-equipped Tryptase test facility.
• With the SST (Serum Separator Tube) tube linked to the hand, a blood sample will be taken.
• Before being submitted to the research lab for analysis, the blood sample tube is shaken to remove serum from the clot