Androgen Receptor (AR) Gene Analysis Test Cost & Procedure

The androgen receptor (AR), also understood as NR3C4 (nuclear receptor subfamily 3, group C, component 4), is a precise sort of nuclear receptor that is turned on by attaching to another androgenic hormone, like as testosterone and dihydrotestosterone, the cytoplasm and then transmitted into the nucleus. Progestins can obstruct the androgen receptor since they are almost identical to the progesterone receptor and the androgen receptor is most near attached to it.

The androgen receptor has several various roles in expansion to its primary part as a DNA-binding transcription characteristic that supervises gene expression. The association and preservation of the male sexual phenotype rely on androgen-regulated genes.

Clinical importance

The HPA and HPG axis is impacted by high androgen receptor expression, which has been associated with aggression and sex drive.

Prostate cancer may advance due to abnormal androgen receptor coregulator function.

Normal Operation

A protein understood as an androgen receptor is created according to teachings from the AR gene. Normal male sexual expansion before birth and during puberty relies on androgens, which are hormones example testosterone. The body may react properly to these hormones thanks to androgen receptors. Several of the tissues in the body contain receptors, where they attach to (bind to) androgens. To control the activity of androgen-responsive genes, the resultant androgen-receptor complex attaches to DNA. The androgen receptor aids in controlling the development of male sexual characteristics by activating or inactivating the appropriate genes. In addition to controlling hair growth and sex desire, androgens and androgen receptors serve other crucial roles in both men and women.

The Androgen Receptor Test Definition

Dehydroepiandrosterone sulfate and 17-hydroxyprogesterone levels in the blood are measured during the test. It aids in the diagnosis and confirmation of polycystic ovarian syndrome and infertility. The test is also utilized before, during, and after the treatment of polycystic ovarian syndrome and infertility.

Uses

It is taken to the lab for analysis of the blood sample. Dehydroepiandrosterone sulfate results should be between 270 and 1070 ng/dl, and 17-hydroxyprogesterone results should be between 15 and 70 ng/ml.

Procedure

Your doctor will gather the sample and analyze ittourthe tToer to fill the vein with blood and cause it to swell up, your doctor or the lab technician will apply a plastic band to your upper arm before the blood test. The region will then be cleaned with an antiseptic before a needle is inserted. Then he will draw blood and store it in a tube or vial. A bandage is put on the region to halt the bleeding after the plastic band and needle are taken off. Generally, the full technique seizes a few minutes.