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Anti-GBM antibody testing is crucial since it provides a diagnosis and directs treatment—chest x-ray link, which can also aid in detecting any lung damage.
Anti-GBM antibodies; human glomerular basement membrane antibody; GBM antibody test. They may lead to kidney damage.
Surgery is the cornerstone of GBM treatment, followed by radiation and chemotherapy. Surgery's main goal is to cut off as much of the tumoras possible without harming the healthy brain tissue that surrounds it and is necessary for regular neurological function.
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For a chest X-ray or CT scan to check for lung damage.
Glomerulonephritis with or without pulmonary bleeding and circulating anti-glomerular basement membrane (anti-GBM) antibodies are referred to as "Goodpasture illness."
Definition. Anti-glomerular basement membrane illnesses (anti-GBM diseases) are rare conditions that can cause lung and kidney disease to deteriorate rapidly. Certain variations of the illness affect the kidney or lungs. She was formerly known as having Goodpasture syndrome, an anti-GBM illness.
The rare autoimmune illness known as anti-glomerular basement membrane disease (anti-GBM disease) causes glomerulonephritis to proceed very quickly. IgG autoantibodies against the non collagenous portion of the 3(IV) collagen chain typically mediate this condition. IgA or IgM anti-GBM antibodies are occasionally involved.
Glomerular basement membrane (GBM) antibodies are used with a clinical history and physical exam to diagnose Goodpasture syndrome when there is a fast development of pulmonary bleeding or renal failure. Goodpasture syndrome is associated with positive GBM antibody test results.
An autoimmune condition known as anti-glomerular basement membrane disease (anti-GBM) most frequently manifests as progressing glomerulonephritis with or without pulmonary involvement. Antibodies against antigenic targets located inside the basement membranes of the glomeruli and alveoli are present, which defines the condition.
The condition develops due to the immune system's erroneous production of antibodies against collagen in the kidneys and lungs. A protein called collagen aids in the formation of connective tissue. Initial Goodpasture syndrome symptoms include vague ones like weariness. However, it can quickly affect the kidneys and lungs.
We advise treating most patients with the anti-GBM disease with plasmapheresis in addition to prednisone and cyclophosphamide.
Test Type | Anti-Glomerular Basement Membrane (GBM) Antibody by ELISA |
Includes | Anti-Glomerular Basement Membrane (GBM) Antibody by ELISA (Pathology Test) |
Preparation | |
Reporting | Within 24 hours* |
Test Price |
₹ 1250
|
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