Antinuclear Antibody (ANA) IFA Reflex Blot Test Cost & Procedure

To identify antinuclear antibodies in the blood and help diagnose autoimmune diseases, request this ANA Screen, IFA, and Blood Test, with Reflex to Titer and Pattern. Autoantibodies, on the other hand, incorrectly trigger the immune system to attack the body, as opposed to different antibodies that defend the body against illnesses like viruses or bacteria.

Because they specifically target the nucleus of healthy cells, these antibodies are anti-nuclear." The nucleus, which transmits signals to activate vital cell processes, acts as the cell's control centre.

However, ANAs mistakenly label healthy proteins in the nucleus as foreign and dangerous, leading to inflammation and the body attacking itself.

People can order an ANA-IFA Blood

Test to help in the diagnosis of autoimmune illnesses, such as:

• Lupus erythematosus systemic
• Sjogren's disorder
• Dermatomyositis and polymyositis
• Idiopathic juvenile arthritis
• Raynaud's syndrome
• lupus caused by drugs
• the disease of several connective tissues
• Hepatitis auto-immune.

When is this test recommended?

If someone exhibits symptoms of an autoimmune illness, they may request an ANA-IFA Blood Test. The following are typical signs of autoimmune diseases:

• FeversRash
• Fatigue

swelling and pain in the joints or inflammation

• muscle ache

stomach aches or digestive problems

• enlarged glands.

What do the findings indicate?

An autoimmune condition is improbable if autoantibodies were not found in the person's blood, according to a negative ANA result.

• A positive ANA test, however, may imply that autoantibodies were found in the patient's blood sample. However, it should be noted that positive ANA results do not always imply that an individual has an autoimmune illness.
• A viral infection, specific drugs, and other medical disorders like cancer can all influence ANA production.
• Consequently, to screen for an autoimmune condition, healthcare professionals consider a patient's ANA test results, symptoms, physical exams, and another lab testing.
• An antibody titer test, which counts the number of antibodies in the blood and reports it as a ratio, such as 1:160, is also included in this ANA-IFA blood test.

Uses:

The minimal titer ratio considered to be a positive result is indicated by the reference range, which can vary between laboratories.

• This test also records the staining patterns that the antibodies created.
• Although specific patterns may be linked to particular diseases, the designs cannot definitively diagnose a health condition.
• These patterns may also help medical professionals identify the type of ANA in a patient's blood and suggest whether further testing is necessary.
• The most often observed patterns are as follows:
  • Homogenous
  • Speckled
  • Centromere
  • Nucleolar