Arylsulfatase B (ARSB) C3 Test Cost & Procedure

An enzyme-linked to mucopolysaccharidosis VI is called arylsulfatase B (also known as N-acetylgalactosamine-4-sulfatase, chondroitin sulfatase, acetylgalactosamine 4-sulfatase, and N-acetylgalactosamine 4-sulfate phosphohydrolase) (Maroteaux–Lamy syndrome).

Why is this advised?

• Complex compounds within a cell are disassembled by lysosomal enzymes (acid hydrolases).
• The breakdown products are then either recycled or removed from the cell. Any one of these enzyme deficiencies will result in a "storage disease," which is typically accompanied by developmental regression.
• The clinical signs of various storage illnesses can be identical, thus it might be required to evaluate the activity of several distinct enzymes before identifying the one that is lacking in a given patient.
• If desired, these tests can also be ordered exclusively.
• The following enzymes are included in the white cell enzyme screen:
  • arylsulfatase
  • A, -fucosidase (Fucosidosis)
  • Galactosidase (Fabry disease)

The tri potassium phenolphthalein disulfate substrate is attacked by the arylsulfatase enzyme, which is produced by different Mycobacterium species. The medium turns red as a result of the reaction that releases phenolphthalein.

Preparation for the Arylsulphatase A:

• Your doctor will also need your permission.
• Additionally, you must disclose to your doctor your medical history, current medications, and any recent operations.
• You simply need to confirm that you have acquired the necessary data.
• You could be requested to collect the first urine of the day for the urine test.
• Your doctor would inform you if anything additional was necessary.
• Your physician will provide you with advice based on your circumstances and state of health.

Arylsulphatase A Test Applications;

• The range of the test's normal results for 4-pyrocatechol is 32.0 to 129.6 nanomoles/ml of serum/4 hours.

Procedure:

• Your doctor will gather and analyze the material for the test.
• Your doctor or the lab technician will put a plastic band on your upper arm before totyoull the vein with blood and causing it to bulge.
• After using an antiseptic to disinfect the region, a needle will be inserted.
• The blood sample will then be collected and placed in a vial or tube.
• The needles are removed, and the region is then wrapped to halt the bleeding.