Autoimmune Liver Disease Profile - 1 Test Cost & Procedure

Panel for autoimmune liver disease

 A series of tests called an autoimmune liver disease panel are run to look for the condition. An autoimmune liver disease occurs when the immune system attacks its own cells of the liver.

These tests consist of:

• Antinuclear antibodies (ANA)
• Perinuclear antineutrophil cytoplasmic antibodies (p-ANCA)
• Anti-smooth muscle antibodies (anti-SMA)
• Anti-mitochondrial antibodies (AMA)
• Anti-soluble liver antigen / liver pancreas antibodies (anti-SLA/LP)
• Anti-Liver-Kidney microsome 1 antibodies (anti-LKM1)
•  Anti-Liver-Kidney microsome 3 antibodies (anti-LKM3)
•  Anti-Liver Cytosol 1 Antibodies (anti-LC1)

Other tests can be on the panel as well.

Immune protein levels in the blood are frequently examined as well.

Diagnostic criteria for the two different kinds of autoimmune hepatitis include typical autoantibody patterns.

Autoimmune liver disease profile 1

The presence of ANA, ASMA, LKM1, and AMA in Autoimmune Liver Disease Profile 1/Autoimmune Hepatitis 1 facilitates the early diagnosis of autoimmune hepatitis and Primary Biliary Cirrhosis. A collection of illnesses known collectively as autoimmune liver disease occur when the immune system unintentionally targets the liver. This damages the liver cells and causes inflammation, causing varying degrees of liver injury.

Autoimmune Liver Disease Types

There are two recognised types of autoimmune hepatitis.

It's more likely that type 1 autoimmune liver disease will be prevalent. The majority of those who have type 1 autoimmune hepatitis may also also have other autoimmune diseases such celiac disease or ulcerative colitis.

Adults, particularly kids and young adults, can develop type 2 autoimmune liver disease. Several underlying autoimmune health issues may coexist with this type of autoimmune illness.

Autoimmune liver disease

There are various forms of autoimmune liver disease, however the following are the most prevalent:

The symptoms of autoimmune hepatitis (AIH), which include cirrhosis, jaundice, exhaustion, abdominal discomfort, and itchy skin, include inflammation and the death of liver cells.

Primary biliary cholangitis (PBC) is a condition marked by inflammation of the tiny bile ducts and hepatic damage. This causes the flow of bile to get obstructed, which ultimately causes cirrhosis, jaundice, and itching. Primary sclerosing cholangitis (PSC) is characterised by bile duct inflammation and scarring both inside and outside the liver. This can cause bile duct obstruction, which can cause cirrhosis, jaundice, and itching.