Beta-Catenin Test Cost & Procedure

This test helps identify and diagnose all lesions and diagnose Desmoid type Fibromatosis. For diagnosis, certain soft tissue cancers, such as fibromatosis and endometrial stromal sarcoma, can be identified by aberrant nuclear staining.

What exactly is beta-catenin?

An essential regulator of embryogenesis and cell-cell adhesion is beta-catenin. Several types of human cancer may result from beta-catenin mutations. Beta-catenin membrane staining indicates normal cells, while cytoplasmic and nuclear staining indicates aberrant cells. Gardner syndrome is characterised by beta-catenin dysregulation, which results in familial adenomatous polyposis and fibromatosis. Beta-catenin is also found in the nuclei of other sarcomas, including synovial sarcoma, osteosarcoma, liposarcoma, palisaded myofibroblast oma, and colon and endometrioid ovarian carcinomas.

What is the Beta Catenin Test, or IHC?

A test used to find mutations in the Beta Catenin gene is the IHC Beta Catenin test. Moreover, it aids in embryo development and cell adhesion. The adenomatous polyposis coli (APC) protein controls the amounts of eta-catenin in the blood. Beta Catenin can accumulate or increase unnaturally and can cate tumours in the soft tissues of many different organs, such as the lungs, pancreas, and ovaries. Variation in this protein or the Beta Catenin can cause these abnormalities.

Preparation for the IHC and Beta Catenin Test:

• The test doesn't require any extra preparation. IHC and Beta Catenin Tests
• When Beta Catenin levels are normal, only the membrane is stained. There is also nuclear staining or staining of the cell cytoplasm in cases of diseased tissues.

Process for the IHC and Beta Catenin Test:

Patients' tissue samples are taken via biopsy or other techniques. The materials are examined on slides after being encased in paraffin wax. It involves tissue immunohistochemistry. The immunoreactivity, or how the immune system reacts to an antigen, is gauged by the prepositively positive stain stain stain intensity and is measured by the number of degraded proteins in the cytoplasm and nucleus of the cells or tissues.