Types of Jaundice Disease

Suffering from Jaundice fever? Know all about the types and symptoms of Jaundice and how to diagnose and prevent Jaundice disease.

What is Jaundice

Jaundice is a yellowish discoloration of the body tissues that result from deposition of bilirubin.

The tissue deposition of bilirubin would occur only in the presence of any serum Hyperbilirubinemia, which could be a sign of liver disease.

Key Facts:

Prevalence of jaundice in adults is considered to be rare, while jaundice in babies is considered common, with an estimation of 80% affected during their first week of life.
Severe jaundice in babies which is not treated in time can cause brain damage. The baby must be checked for the level of jaundice in hospital and again within 48 hours after you have left the hospital.

There are four types of Jaundice:

Pre-Hepatic Jaundice
Hepatic Jaundice
Post-Hepatic Jaundice
Neo-Natal Jaundice

Production and Metabolism of Bilirubin

It is a tetrapyrrole pigment, which is a breakdown product of heme.

About around 80-85% of the 4mg/kg body weight of bilirubin produced daily is a breakdown of the hemoglobin in senescent RBCs.

Remainder- from erythroid cells in bone marrow and turnover of hematoproteins, such as myoglobin and cytochromes that are found in the tissues throughout the person’s body.

Symptoms of Jaundice

Yellow colored skin
Yellow eyes (Conjunctiva)
Itching all over the body
Dark urine and light-colored stool
Belly Pain
Tiredness

Cholestatic Conditions That May Produce Jaundice

Viral Hepatitis

Alcoholic Hepatitis

Drug Toxicity e.g. chlorpromazine

Sarcoidosis

Paraneoplastic syndrome

Diagnosis of Jaundice

	Pre-Hepatic jaundice	Hepatic jaundice	Post-Hepatic Jaundice
Total serum bilirubin	Normal / increased	Increased	Increased
Conjugated bilirubin	Normal	Increased	Increased
Unconjugated bilirubin	Normal / increased	Increased	Normal
Urobilinogen	Normal / increased	Decreased	Decreased / negative
Urine color	Normal[39]	Dark (urobilinogen, conjugated bilirubin)	Dark (conjugated bilirubin)
Stool color	Brown	Slightly pale	Pale, white
Alkaline phosphatase levels	Normal	Increased	Highly increased
Alanine transferase and aspartate transferase levels	Normal	Highly increased	Increased
Conjugated bilirubin in urine	Not present	Present	Present

Imaging Modalities

Medical imaging modalities for the following:

Ultrasound
CT scan
HIDA scan (helpful in bile-duct blockage)

Differential diagnosis

The yellow discoloration of patient’s skin, especially on patients palms and soles of the patient, due to the cause carotenemia—this is considered to be harmless condition

Hypercupremia
Wilson's Disease
Metabolic Derangement
Kayser-Fleischer Ring

Complications of Jaundice

High level of patient’s bilirubin could be toxic and also lead to the rare type of the brain damage; this is called kernicterus in some infants.

Treatment of Jaundice

The Treatment would depend on the patients underlying cause in jaundice disease.

Warm baths
Take the drug antihistamines for mild pruritis.
For moderate to even severe pruritis, drugs such as cholestyramine or colestipol are used.
In some cases, irreparable damage to the kidneys could also lead to the need for Liver Transplant.

Prevention of Jaundice

Lifestyle Changes are recommended for bringing about a difference in patients health.This includes the following:

Consuming Balanced Diet
To Exercise Regularly
To Limit Your Alcohol Consumption
To Avoid Toxic/Harmful Chemicals( Inhaled And Touched)
To Manage The Medications Carefully

Why Ganesh diagnostic and Imaging Centre should be your preference to screen you for Jaundice?

At Ganesh Diagnostic and Imaging Centre, we are known for providing excellent service and care to its patients for decades. Lakhs of satisfied patients over the years!

It is an established and renowned diagnostic centre since 2001.

Their excellence is backed by NABH and NABL Accreditations.

NABH accreditation is proof of highest standard of care and service provided to the patients. NABL accreditation reflects the competency of laboratories and equipment based on some national and international standards.

Test report is available digitally too.

Ganesh Diagnostic and Imaging Centre is a one-stop solution for getting all kinds of tests done, as all services are available under one roof.

The aim of GDIC is to provide world’s finest technology at the lowest price.

The rates of scans are reasonably priced. Ganesh Diagnostic and Imaging Centre also offer FLAT 50% OFF on many tests.

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References:

https://en.wikipedia.org/wiki/Jaundice
https://www.cdc.gov/ncbddd/jaundice/index.html
https://www.medicalnewstoday.com/articles/165749
Harrison’s Principles of Internal Medicine, 20 th edition, Volume 1

Note from Ganesh Diagnostic & Imaging Center

Early checkups are always better than delayed ones. Safety, precaution & care are depicted in the several health checkups at our center.
Here, at Ganesh Diagnostic and Imagining Center, we present simple & comprehensive health packages for any kind of testing to ensure the early prescribed treatment to safeguard your health.
So, visit us at the earliest to ensure good health and to maintain an active immune system.