In fetus, both sets of ducts are present: Mullerian ducts as well as Wollfian ducts. Anti Mullerian Hormone and Testosterone are secreted by testes in fetus having XY chromosomes. The cumulative effect of AMH and testosterone...
What is AMH and what is the role of AMH?
AMH stands for Anti Mullerian Hormone.
Mullerian ducts – these are paired tubular structures of embryo, which grow into female reproductive structure in the later stages of development.
Wollfian ducts – these are also paired structure found in embryo, which develops into internal male reproductive system in the later stages of embryonic development.
In fetus, both sets of ducts are present: Mullerian ducts as well as Wollfian ducts. Anti Mullerian Hormone and Testosterone are secreted by testes in fetus having XY chromosomes. The cumulative effect of AMH and testosterone in fetus is to suppress the development of Mullerian ducts into internal female reproductive organs.
In fetus having XX sex chromosomes, the development of Wollfian ducts into the internal male reproductive system does not take place due to absence of testosterone hormone.
Role of AMH in fetus
It plays an important role in the suppression of female reproductive parts development in fetus with XY sex chromosomes. Hence, it is also called Mullerian Inhibiting Factor or Mullerian Inhibiting Hormone.
Role of AMH in adults
The secretion of AMH in males and females after birth is not uniform and alike. A different pattern of secretion in males and females is observed.
Pattern of AMH levels in males: the levels of AMH in male infants is high, to promote development of Male reproductive system. The levels of AMH remain as such up until puberty, after which the levels of AMH in males start declining.
Pattern of AMH levels in females: the levels of AMH in infants are negligible, so as to promote the development of Mullerian duct to female reproductive system. The levels remain as such up until puberty. At puberty, the follicles start producing AMH in females and the highest level is seen during this time only (if any medical condition is not present such as PCOD). These levels start declining gradually as females advance in age and drop to negligible at menopause.
What is the clinical significance of fluctuation of normal AMH levels in males vs. females?
Low levels of AMH in Infants with XY sex chromosomes (males)
AMH levels are supposed to be high in infants with XY chromosomes. If the levels are not sufficient, it can lead to poor development of male reproductive organs.
In such cases, the Mullerian ducts do not disappear, as a result of which the testes remain un-descended (Cryptorchidism). The outer genitals appear ambiguous in such cases.
The testes are present, but have not descended resulting in low sperm count in such cases.
Low Levels of AMH in Females after puberty
With the onset of puberty in females, ideally the level of AMH should increase and attain a normal maximum level for certain initial years of puberty.
It happens because the follicles start producing and secreting AMH hormones.
As females advance in age, the ovarian reserve starts depleting, and the levels of AMH drops gradually with age. Hence, levels of AMI in females along with estimation of other hormones, helps in estimating fertility and chances of conception. It estimates indirectly amount of ovarian reserve left.
AMH plays an important role in secretion of Follicle Stimulating Hormone (FSH) and Luteinizing Hormone (LH) in females, hence has a role in ovulation of follicles and overall fertility.
Low levels of AMH in adult females can indicate towards early onset of menopause in females.
Consequently, low levels of AMH in females are also taken as an indication of infertility.
Very high levels of AMH in Females after puberty
Two suspected clinical conditions can lead to very high levels of AMH in adult female:
In case of PCOD, level of AMH is very high.
In case of ovarian cancers, elevated level of AMH is seen.
What is AMH test and what will the result infer?
AMH test is done to estimate the levels of Anti Mullerian Hormone in blood sample. AMH test result infer different things in different individuals, for example-
In adult females, AMH levels act as a marker for determining the remaining ovarian reserve.
In infants, AMH level are tested in case of ambiguous outer genitals, along with other diagnostic tests to identify male or female.
AMH levels are also used as biomarkers for PCOD and ovarian cancers.
When is AMH test done?
Your doctor will prescribe an AMH test in the following conditions:
- Infants having ambiguous outer genitals
- Adult females who are unable to conceive
- Adult females undergoing IVF or any other fertility treatment for pregnancy
- In case of suspected ovarian cancer
- To assess ovarian reserve after chemotherapy (cancer treatment) for chance of pregnancy in future
- In females getting examined for menopause
How is AMH test performed?
Blood sample is taken from vein in arm of the individual by a healthcare professional with the help of a needle. The blood sample is labeled properly to avoid confusion and mixing of samples. The sample is sent to lab for testing.
Where to get AMH test done in Delhi NCR?
There are many good options available in Delhi NCR for getting AMH test done. However, the best lab for AMH test as well as many other diagnostic tests done is Ganesh Diagnostic and Imaging Centre. For us, patients come first, hence, patient’s safety and care is our priority!
How much does AMH test cost in Delhi NCR?
The price of AMH test in Delhi NCR varies from lab to lab. The price may also vary upon the type of AMH test. To get the best deal on getting AMH test in Delhi NCR, visit Ganeshdiagnostic.com
Currently, Ganesh Diagnostic and Imaging Centre is offering FLAT 50% discount on many tests.
AMH tests available at Ganesh Diagnostic and Imaging Centre:
Anti Mullerian Hormone (AMH) Basic Panel at 1800 900 INR
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Anti Mullerian Hormone at 1850 INR
Anti Mullerian Hormone (AMH) Plus at 2160 1080 INR
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Infertility Panel 3 at 7500 3750 INR
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Infertility Comprehensive Profile – Female at 2399 1200 INR
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Ovarian Reserve Panel at 3030 1515 INR
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Why Ganesh Diagnostic and Imaging Centre is the best choice?
Ganesh Diagnostic and Imaging Centre is an established and renowned diagnostic centre since 2001.
It is known for providing excellent service and care to its patients for decades.
Ganesh Diagnostic and Imaging Centre have NABH and NABL Accreditations, which serve as the proof of their professionalism.
NABH accreditation is given to those hospitals and diagnostic centers which have the highest standard of patient care and service, whereas NABL accreditation is given for competency of laboratories and equipment based on certain national and international standards.
The facility for Pathology testing operates 24x7, 365 days, providing service to the patients round the clock!
Provision of Home sample collection is also there, free of any additional cost. It enables the patients to get tests done in the comfort of their homes.
Samples are collected in a hassle-free manner, labeled correctly and transported back to the lab safely while taking all precautions.
Test report is generated within 24 hours of sample collection. Reports are available digitally and can be downloaded from the website.
Ganesh Diagnostic and Imaging Centre is a one-stop solution for getting all kinds of tests done, as all services are available under one roof.
The goal of GDIC is to provide world’s finest technology at the lowest price. Therefore, the rates of tests are reasonably priced. Ganesh Diagnostic and Imaging Centre also offer flat 50% off on many tests.
Patients can rely upon test reports as reports are 100% accurate.
The staff at Ganesh Diagnostic and Imaging Centre is skilled and absolutely professional.
Ganesh Diagnostic and Imaging Centre is empanelled with various prestigious government and private organizations such as:
- ESIC
- CGHS NHA
- NCDC
- NDMC
- DGEHS
- ECHS
- DELHI JAL BOARD
- DAK
- RAILWAYS
- BSES YAMUNA/ RAJDHANI POWER LTD
- SANJAY GANDHI HOSPITAL
- TATA POWER LTD
- BABA SAHEB AMBEDKAR HOSPITAL
- BJRM HOSPITAL
- ICAR
- BHAGWAN MAHAVIR GOVERNMENT HOSPITAL
- MINISTRY OF HOME AFFAIRS
For more information regarding panels, click here!
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Frequently Asked Question related to AMH test:
Is there any preparation required for AMH test?
No, there is no preparation required for getting AMH test done. Fasting is not required and this test can be done at any point of your menstrual cycle as this hormone (AMH) does not show fluctuating levels like other hormones during different stages of menstrual cycle.
Are there any risks in getting AMH test?
No, there are no possible risks involved in getting AMH test. AMH test is a non-invasive and safe test. The only trouble in getting this test is the sting of needle felt by the patient while giving blood sample.
What is normal AMH level?
The classification of normal levels of AMH differs for different individuals. It depends on gender, age, medical history. Following table can be used as a reference for adult females, although for getting correct diagnostic advice, consults your doctor.
|
High level of AMH |
Over 4.0 ng/ml |
|
Normal level of AMH |
1.5-4.0 ng/ml |
|
Low Normal level of AMH |
1.0-1.5 ng/ml |
|
Low level of AMH |
0.5-1.0 ng/ml |
|
Very low level of AMH |
Less than 0.5 ng/ml |
What is AMH level for fertility?
Although it is difficult to classify, normal level depend on various factors such as age and medical history of patient. But for reference, 1.0-4.0 ng/ml is considered normal level of AMH for fertility.
How can I increase my AMH naturally?
Consumption of the following food items has shown to increase AMH level naturally:
- Green leafy vegetables
- A variety of dry fruits, for example, almonds
- Garlic
- Eggs
- Pumpkin seeds
Vitamin – D deficiency has been linked to low levels of AMH. Hence, consuming Vitamin – D supplements can improve AMH levels.
