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Globulin Functions: Test, Importance and Procedure

Globulin Functions: Test, Importance and Procedure

A globulin test measures these protein levels, helping diagnose various health conditions, including liver and kidney diseases, and immune system disorders.

Globulins are proteins present in our blood serum. They are also classified into three types: alpha globulins, beta globulins, and gamma globulins. These proteins play vital roles in our body such as immune response (resistance against infection), blood clotting, and liver and kidney functions.

Various globulins have various size and structure and they also perform different functions:

  • Alpha globulin: aids in the transport of vitamins and hormones.
  • Beta globulin: involved in the transport of hormones and helps blood to clot.
  • Gamma globulin: antibodies that have a major role in the immune system.

Alpha and beta globulin are produced in the liver and gamma globulin is synthesized in lymphoid tissues.

A globulin test is used to measure blood levels of globulin protein and it aids in the diagnosis of numerous conditions, this test gives information about different health conditions which result in early diagnosis. Due to its significant role in our health, examination of any alteration in globulin level can give information about other medical conditions. Regular testing of globulin aids in monitoring different diseases.

Purpose of Globulin Test:

Globulin Blood test is utilized for multiple purposes. It allows doctors to gauge the overall state of the patient, identify particular diseases and monitor the progression of chronic diseases. 

Why is a Globulin test important ?

  • To check the liver function

Liver produces two kinds of globulin, if the liver gets infected or damaged, production of globulin is also impacted. Low globulin level is connected with diseases like hepatitis, cirrhosis and fatty liver. Liver damage may result in higher levels of globulin, it occurs when the liver cannot efficiently degrade certain proteins. Globulin test is a component of the Liver function test, which is employed to locate any abnormality in the liver.

  • Functioning of the immune system

Gamma globulin or Immunoglobulin (Ig), gamma globulin acts as an antibody within the immune system and helps the body to fight infection. Fluctuation in Ig globulins warns us of immune system disorders such as immune deficiency disorders like HIV or autoimmune disorders like Rheumatic arthritis.

  • Damaged kidney

Kidneys remove waste from the blood, it contains proteins. In nephrotic syndrome, protein is not filtered and is excreted in the urine, causing decreased blood globulin levels. This test is used to identify kidney problems and is included in the kidney function test profile.

  • General Health check-up

As part of routine check-ups, a globulin test is conducted. It assists us in finding the overall protein level.

Procedure of Globulin Blood Test:

This test is conducted in laboratory and clinical environments, the process begins with taking a sample from the vein. There is no special preparation needed for this test, at times this test is conducted alongside other tests such as KFT and LFT. Fasting may be advised prior to the test.

 

Blood sample taking, The area from which the sample would be taken is cleaned by the healthcare professional. Needle is pierced into the vein to take a blood sample and then this sample is analyzed in a laboratory. The value of globulin test is indicated in Gram per deciliter (g/dL) and the normal value is usually between 2- 3.5 g/dL. This may differ with age and gender.

Cost

Other tests of Globulin Blood Test- 

Click here to know all the tests related to the Globulin test that are necessary. 

Frequently Asked Questions 

Q. What is Globulin?

Globulins are a class of proteins present in our blood serum that carry out critical functions in our body, like immune response(fighting infection), blood clotting, functioning of liver and kidneys etc.

Q.  What are the Various Functions of Globulin?

Different globulin functions are the immune response, blood clotting and the boost in liver and kidney function etc.

Q. Which tests are used for Globulin Diagnosis?

Blood tests such as serum protein electrophoresis (SPEP) are employed for estimation of globulins.

Q.  Where are Globulin Tests done in Delhi?

Patients can select Ganesh Diagnostic Centre for any kind of Globulin test at discounted prices.