LFT Blood Test: A Comprehensive Guide

What is LFT?

LFT stands for Liver Function Test, which is a diagnostic tool used to detect the presence of certain substances or biomarkers in a sample. LFTs are commonly used in medical, research, and industrial settings for various applications, including disease diagnosis, pregnancy testing, drug testing, and environmental monitoring. The basic principle behind LFTs is the use of specially designed test strips or devices that contain specific reagents, such as antibodies or enzymes, which interact with the target substance of interest. The sample, often a bodily fluid like blood, urine, or saliva, is applied to the test strip, and the results can be observed within a short period, typically minutes. LFT is also known as liver panel or liver enzyme test which help evaluate various liver-related parameters.

Gamma-glutamyl transferase (GGT) is a liver enzyme test that measures the levels of GGT in the blood. GGT is primarily found in the liver, but it is also present in other organs such as the kidneys, pancreas, and gallbladder. The GGT test is often included as part of the liver function panel or liver enzyme tests.

Why is LFT Done?

Some common reasons why LFT blood tests are done:

Screen for liver diseases: LFTs are often performed as part of routine health check-ups or preventive screenings to identify liver diseases at an early stage.
Monitor liver function: If an individual has a known liver condition or is undergoing treatment that may affect liver function, regular LFTs may be ordered to monitor the liver's health and response to treatment.
Assess liver damage: LFTs can determine the extent of liver damage caused by various factors, such as viral infections (like hepatitis B or C), alcohol abuse, drug toxicity, or autoimmune disorders. Elevated levels of liver enzymes, such as alanine transaminase (ALT) and aspartate transaminase (AST), indicate liver cell damage or inflammation.
The normal ranges for ALT are 7 to 55 units per liter (U/L) for men and 7 to 45 U/L for women, for AST is usually 8 to 48 U/L for men and 7 to 35 U/L for women and, for total bilirubin is typically 0.1 to 1.2 milligrams per deciliter (mg/dL).
Evaluate liver function before surgery or starting medications: Prior to undergoing surgery or starting certain medications, healthcare providers may order LFTs to ensure that the liver is functioning properly.
Monitor side effects of medications: Regular LFTs can help monitor liver function while a person is taking medications, allowing early detection of any drug-induced liver injury.

What conditions are diagnosed by LFT?

LFTs (Liver Function Tests) are a group of blood tests that assess the overall health and function of the liver. Here are some conditions that can be evaluated or monitored using LFTs:

Hepatitis: LFTs can detect liver inflammation caused by various types of viral hepatitis, including hepatitis A, B, and C. Elevated levels of liver enzymes (such as ALT and AST) are often observed in acute or chronic hepatitis.
Fatty Liver Disease: LFTs reports can provide clues about the presence of non-alcoholic fatty liver disease (NAFLD) or alcoholic fatty liver disease, which is because of the high GGT levels. Abnormal liver enzyme levels, along with other diagnostic tests (such as imaging), may indicate fat accumulation in the liver.
Cirrhosis: LFTs are helpful in assessing the extent of liver damage and determining the progression of liver cirrhosis. As cirrhosis develops, liver enzyme levels may become persistently elevated, while albumin (a protein produced by the liver) and clotting factors may decrease.
Biliary Tract Disorders: LFTs can indicate problems related to the bile ducts and gallbladder. Conditions such as cholangitis (inflammation of the bile ducts), gallstones, or bile duct obstruction may cause abnormalities in liver enzyme levels and bilirubin.
Liver Cancer: Although LFTs alone cannot diagnose liver cancer, they may show high levels of LFT or bilirubin, which can be further investigated through imaging studies.
Autoimmune Liver Diseases: Conditions like autoimmune hepatitis, primary biliary cholangitis (PBC), and primary sclerosing cholangitis (PSC) involve immune-mediated inflammation of the liver and bile ducts. LFTs can assist in detecting abnormalities associated with these conditions, including elevated liver enzymes and bilirubin.

LFT Preparation & Procedure

Preparations:

Fasting: In most cases, fasting is not required for LFTs. You can usually have your LFT done at any time of the day, and there is no need to abstain from food or drink before the test. However, it's always a good idea to confirm with your healthcare provider if fasting is necessary in your specific situation.
Medications: Inform your healthcare provider about any medications, supplements, or herbal remedies you are currently taking. Some medications can affect liver enzyme levels, so it is important to disclose this information.
Alcohol and certain substances: Avoid consuming alcohol for at least 24 hours before the test, as alcohol can affect liver enzyme levels.
Physical activity: There are typically no restrictions on physical activity before an LFT, unless advised by your healthcare provider.

Procedure:

Blood sample collection: Liver Panel 1, also known as LFT Serum, is a blood test that assesses various liver-related parameters to evaluate the overall health and function of the liver. The healthcare professional begins by cleaning the site on your arm, usually near the inner elbow, with an antiseptic solution. They will then use a sterile needle to draw a small amount of blood from one of your veins. The needle insertion may cause a brief prick or stinging sensation, but it is generally well-tolerated.
Collection and labeling: The blood sample is collected in a tube or vial. The doctor will ensure that the sample is properly labeled with your name, date of birth, and other relevant identification details to avoid any confusion.
Sample processing: Once the blood sample is collected, it is sent to the laboratory for analysis. In the laboratory, the blood sample is processed to separate the serum or plasma, which contains various markers and enzymes that indicate liver function.
Laboratory analysis: The serum or plasma is analyzed using specific tests to measure liver enzymes and other markers. Common liver function tests include measuring levels of enzymes such as alanine transaminase (ALT), aspartate transaminase (AST), alkaline phosphatase (ALP), and bilirubin. These tests help evaluate the overall health and function of the liver.
Results: Your healthcare provider will interpret the LFT results. These results help to assess liver function, detect any abnormalities, and assist in the diagnosis and monitoring of liver-related conditions which is one such benefit of a LFT Test. Other benefits of the LFT test include Monitoring the progress of liver diseases or conditions, Assessing the effectiveness of treatment, screening for liver-related issues, Evaluating overall liver function.

Understanding Abnormal LFT Results

An abnormal LFT (Liver Function Test) can indicate potential issues with liver health. When the LFT blood test shows abnormal levels or results, it may suggest liver dysfunction or the presence of liver-related conditions. An abnormal LFT report prompts further investigation to identify the underlying cause and develop an appropriate treatment plan. By detecting abnormal LFT levels, healthcare providers can take necessary steps to address liver abnormalities, monitor disease progression, and manage the associated health risks.

LFT Test Price

The cost of an LFT test in India in India ranges from around INR 400 to INR 1500 or more and if someone is looking for LFT test at home, the cost of LFT (Liver Function Test) conducted at home typically falls within the range of 600 to 2000 rupees. The price of LFT (Liver Function Test) can vary depending on several factors, including the location, type of healthcare facility, and any additional tests included in the panel.

Best diagnostic Center for LFT in Delhi

When it comes to Liver Function Tests (LFTs) in Delhi, Ganesh Diagnostic and Imaging Centre stands out as the best diagnostic lab in Delhi, and for those too who are searching for affordable and reliable LFT testing near their location. Whether you're searching for the best diagnostic center for LFT tests, or specifically looking for a diagnostic lab specializing in LFT tests, Ganesh Diagnostic and Imaging Centre is the ideal choice. Not only does Ganesh Diagnostic and Imaging Centre offer accurate and precise LFT services, but they also provide competitive pricing for individuals seeking the best value for their money. With their state-of-the-art facilities and a team of experienced professionals, Ganesh Diagnostic and Imaging Centre ensures that patients can conveniently buy or book an LFT test near them. The center's commitment to quality control and efficient service makes it the top choice for individuals in Delhi who want to book an LFT test near their location.