Login

Primary Central Nervous System Lymphoma (PCNSL): Symptoms, Causes and Tests

Primary Central Nervous System Lymphoma (PCNSL): Symptoms, Causes and Tests

This article will discuss Primary Central Nervous System Lymphoma (PCNSL), its symptoms, causes and tests. We will also discuss some common questions related to PCNSL.

What is the Primary Central Nervous System (PCNSL)?

Primary central nervous system lymphoma (PCNSL) is known to be an aggressive type of lymphoma that affects the central nervous system (CNS). PCNSL is also known as reticulum cell sarcoma, diffuse histiocytic lymphoma and microglioma. This is the type of non-Hodgkin lymphoma affecting the brain, spinal cord and cerebrospinal fluid. This lymphoma is considered a highly malignant tumour as compared to other types of brain cancer and requires methotrexate-based high doses as primary chemotherapy treatment.

What are the Various Symptoms of Primary Central Nervous System Lymphoma (PCNSL)?

There are various symptoms of Primary Central Nervous System Lymphoma (PCNSL) which are listed below:

  • Headaches, seizures and neurological deficits.
  • Vomiting, nausea and vision problems.
  • Paralysis or weakness in legs and arms.
  • Numbness, abnormal balance movement and difficulty in walking.
  • Always in confusion and difficulty in remembering things.
  • Behaviour changes, personality changes and not being able to make decisions.
  • Hearing loss, Double vision blurry vision etc.

Other symptoms include back pain, bladder and bowel dysfunction etc.

What is the probable reason for Primary Central Nervous System Lymphoma (PCNSL)?

There is no known cause of PCNSL lymphoma, but there are some factors that can increase the risk of developing the condition.

Here are some of the risks that can develop the condition of the PCNSL:

  • Due to the immune system weakening and can happen through various infections and diseases like HIV/AIDS, chronic disorders and immune disorders of the body.
  • The risk of PSNCL increases with organ transplants, people with different transplants increase the risk of developing PSNCL.
  • Drugs and medications that are used to suppress the immune system to treat autoimmune diseases of the body. 

Which tests are used for Primary Central Nervous System Lymphoma (PCNSL) Diagnosis?

Other tests include:

  • Flow cytometry
  • Bone marrow samples
  • Immunohistochemistry
  • Chromosome Analysis

Conclusion

Primary central nervous system lymphoma (PCNSL) is known to be an aggressive type of lymphoma that affects the central nervous system (CNS). PCNSL is also known as reticulum cell sarcoma, diffuse histiocytic lymphoma and microglioma. There are various signs of Primary Central Nervous System Lymphoma (PCNSL) Behavioural changes, personality changes, not being able to make decisions, Hearing loss, Double vision blurry vision etc. The causes include a weakened immune system, organ transplant, immunosuppressants etc. There are various tests used to diagnose PCNSL like PET, MRI, CT, blood tests, biopsy etc.

Frequently Asked Questions (FAQs)

What is the Primary Central Nervous System Lymphoma (PCNSL)?

Primary central nervous system lymphoma (PCNSL) is known to be an aggressive type of lymphoma that affects the central nervous system (CNS). PCNSL is also known as reticulum cell sarcoma, diffuse histiocytic lymphoma and microglioma. 

What are the Various Symptoms of Primary Central Nervous System Lymphoma (PCNSL)?

There are various symptoms of primary central nervous system lymphoma (PCNSL). Behavioural changes, personality changes, not being able to make decisions, Hearing loss, Double vision blurry vision etc.

What is the probable reason for Primary Central Nervous System Lymphoma (PCNSL)?

Various causes of primary central nervous system lymphoma (PCNSL) include a weakened immune system, organ transplant, immunosuppressants etc. 

What is the ICD-10 code for Primary Central Nervous System Lymphoma (PCNSL)?

The ICD-10 code for Primary Central Nervous System Lymphoma (PCNSL) is C83.390.

How to book an online appointment for a Primary Central Nervous System Lymphoma (PCNSL) test in Delhi?

Patients can call at 011-47-444-444 / 011-47-333-333 or visit Ganesh's diagnostic website to book an appointment for Primary Central Nervous System Lymphoma (PCNSL) in Delhi.

How can Patients download Primary Central Nervous System Lymphoma (PCNSL) Reports Online?

Patients can visit Ganesh's diagnostic website or call at 011-47-444-444 / 011-47-333-333 to download the Primary Central Nervous System Lymphoma (PCNSL) report online.