CBNAAT stands for Cartridge Based Nucleic Acid Amplification Test. It is a qualitative, automated and rapid molecular assay. A different cartridge will be used for each test. CBNAAT machines are available in different sizes...
What is CBNAAT and why is it done?
CBNAAT stands for Cartridge Based Nucleic Acid Amplification Test. It is a qualitative, automated and rapid molecular assay. A different cartridge will be used for each test. CBNAAT machines are available in different sizes and capacities. For example, the smallest one can run one sample at a time (i.e. one cartridge only).
This test is performed in order to diagnose Mycobacterium tuberculosis infection by DNA amplification and detection method.
What samples can be tested in CBNAAT?
Mycobacterium tuberculosis infection in most cases is pulmonary but it has been shown to cause extra-pulmonary infections too. The diagnosis of extra-pulmonary tuberculosis remains a challenge for conventional diagnostic methods. CBNAAT is able to detect pulmonary as well as certain types of extra-pulmonary infections.
For diagnosis of pulmonary infection of tuberculosis following samples can be tested:
- Sputum
- Induced sputum
- Tracheal aspirates
- Bronchoalveolar lavage
For diagnosis of extra-pulmonary infection of tuberculosis, the following samples can be tested:
- Fluids such as Ascitic fluid (excess abdominal fluid), pericardial fluid and pleural fluid
- Gastric lavage
- Lymph nodes
- Pus from abscess/ infectious lesion
- Tissues
- CSF (cerebrospinal fluid)
Following samples are NOT tested for tuberculosis infection in CBNAAT:
- Stool
- Urine
- Blood
What are the advantages of CBNAAT?
There are several advantages of CBNAAT over conventional diagnostic method for tuberculosis, such as:
- It is rapid- detection is complete within 2 hours.
- It is automated, so it is not a labor-intensive process.
- It enables early detection of MTB infection, hence aiding in controlling Multi Drug Resistance Tuberculosis (MDR-TB).
- Simple - molecular tests usually require skilled technicians, but CBNAAT is a simple molecular test
- Robust – can be adapted to ‘point of care’
- Detects pulmonary as well as extra-pulmonary infection
- CBNAAT has the ability to diagnose Rifampicin resistance in MTB infection (Mycobacterium tuberculosis).
- The test has good sensitivity and specificity for pulmonary infections (> 95%) and for extra-pulmonary infections, sensitivity is up to 77%.
How is sputum CBNAAT performed?
CBNAAT Sample collection- A healthcare professional will ask you to collect your sputum sample in a plastic cup. Take 2 deep breaths and cough for sputum sample. Collect at least 5ml sputum.
Sputum liquefaction is done with the help of vortex for some time.
Sample is loaded in the CBNAAT machine for detection, the further steps are automated.
After 2 hours, printable results appear on the machine.
Is there any preparation required for sputum CBNAAT?
No, there is no preparation required for sputum CBNAAT, except for a few things which should be kept in mind:
- It is advised to give first sputum sample in the morning, to minimize food particles and other contaminants in sample.
- It is advised to rinse the mouth with water once, before coughing out sputum sample.
What is the cost of sputum CBNAAT in Delhi NCR?
The cost of tuberculosis detection by CBNAAT varies depending on facility, the kind of CBNAAT machine and the number of repetitions of test required for diagnosis.
Delhi NCR has many great options to choose from when it comes to diagnostics and imaging. But, the best diagnostic centre, which provides world’s best and cutting-edge technology at the lowest possible price is Ganesh Diagnostic and Imaging Centre.
Sputum CBNAAT test is available at Ganesh Diagnostic and Imaging Centre at 50% OFF.
Sputum CBNAAT Gene X-pert at 4000 2000INR
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Why Ganesh Diagnostic and Imaging Centre is the best diagnostic lab for Sputum CBNAAT?
Ganesh Diagnostic and Imaging Centre provide the best service and care to patients.
Here are some of the reasons why Ganesh Diagnostic and Imaging Centre is your go-to diagnostic centre:
Ganesh Diagnostic and Imaging Centre is accredited by NABH (National Accreditation Board for Hospitals and Healthcare Providers) and NABL (National Accreditation Board for Testing and Calibration Laboratories) reflecting the highest standard of quality service to patients, and the competency of the labs based on some national and international standards.
Ganesh Diagnostic and Imaging Centre provide world’s best and cutting-edge technology at the lowest price because patients come first!
The facility for getting Pathology tests done is operational 24x7, 365 days.
Free home sample collection is also available at Ganesh Diagnostic and Imaging Centre.
Test report is also available digitally.
Test reports are generated within 24 hours of sample collection.
Test reports are 100% accurate and reliable.
The staff at Ganesh Diagnostic and Imaging Centre is skilled and absolutely professional.
The rates at Ganesh Diagnostic and Imaging Centre are reasonably priced. Ganesh Diagnostic and Imaging Centre also offer FLAT 50% off on many diagnostic tests.
Ganesh Diagnostic and Imaging Centre are empanelled with various prestigious government and private organizations such as:
- ESIC
- CGHS NHA
- NCDC
- NDMC
- DGEHS
- ECHS
- DELHI JAL BOARD
- DAK
- RAILWAYS
- BSES YAMUNA/ RAJDHANI POWER LTD
- SANJAY GANDHI HOSPITAL
- TATA POWER LTD
- BABA SAHEB AMBEDKAR HOSPITAL
- BJRM HOSPITAL
- ICAR
- BHAGWAN MAHAVIR GOVERNMENT HOSPITAL
- MINISTRY OF HOME AFFAIRS
For more information regarding panels, click here!
Frequently Asked Questions (FAQs) related to CBNAAT:
How long does CBNAAT test take?
After putting a sample in CBNAAT machine, further steps are automated, and the process is completed within 2 hours.
Which disease is tested for by CBNAAT?
Various forms of Mycobacterium tuberculosis infection can be diagnosed by CBNAAT. For example- pulmonary infection, extra-pulmonary infection and Multi Drug Resistance TB infection
What is the difference between CBNAAT and Gene Xpert?
Gene Xpert is the name of instrument system/ machine that is used for CBNAAT procedure.
Is there any risk involved in getting sputum CBNAAT?
No, there are no risks in getting sputum CBNAAT. It is a non-invasive test, so it is safe. Although, there is one thing which should be kept in mind while collecting sputum sample- cough in isolation so as to avoid the possibility of spreading TB through droplets in air. After sample collection, close the lid of the container tightly.
What is sample for CBNAAT test?
TB infection can be pulmonary or extra-pulmonary. Depending on the type of TB infection, the sample is collected.
For diagnosis of pulmonary infection of tuberculosis following samples can be tested:
- Tracheal aspirates
- Bronchoalveolar lavage
- Sputum
- Induced sputum
For diagnosis of extra- pulmonary infection of tuberculosis, the following samples can be tested:
- Fluids such as Ascitic fluid(excess abdominal fluid), pericardial fluid and pleural fluid
- Pus from abscess/ infectious lesion
- Gastric lavage
- Lymph nodes
- Tissues
- CSF (cerebrospinal fluid)
