BRCA1 & BRCA2 Mutation Comprehensive Panel Test Cost & Procedure

This test is used to diagnose people with a high risk of cancer. They usually have a history of cancer.

Mutation

It refers to a non-specific change in the DNA of the chromosome.

It can be

• Insertion
• Duplication
• Insertion

What is the BRCA gene?

It denotes Breast Cancer genes. It helps in the identification of breast cancer. It has an essential role in the repair mechanism. Mutations lead to the development of cancer.

What is Breast Cancer?

In this condition, the breast starts lumping up and spreads further rapidly.

What is the purpose of this test?

The genes BRCA1 and BRCA2 are those proteins that hat is tumour suppressants. These are the factors that are responsible for the cell's normal functioning. If there is any mutation seen in these genes, it increases the chances of cancer in your body. When BRCA1 or BRCA2 genes undergo modification, they destroy the cell walls and lead to cancer. It mainly affects women. In males, prostate cancer is seen.

Why is this test recommended?

• Prostate cancer
• Breast cancer
• Pancreatic Cancer
• Fallopian tube cancer
• Ovarian cancer
• Jewish heritage

When is this test recommended?

• History of breast cancer
• History of ovarian cancer
• History of the family with any cancer

Polymerase Chain Reaction

It is popularly known as Molecular Photocopying. It is a rapid technique to multiply segments of DNA. A commoner can easily afford it as its price is low. This multiplication or copy of DNA is essential for genetic analysis.

Uses

In this, the copied DNA is used for various procedures

• Mapping techniques
• Genome project

This test is used to help in the detection of Genetic disorders.