CD19 Flow Cytometry Absolute Count Test Cost & Procedure

The B4 B-lymphocyte surface antigen is another name for CD19. Except for plasma cells, practically all B cells express the CD19 molecule. Moreover, follicular dendritic cells contain it. In B cell development, proliferation, and eventual antibody production, CD19 plays a crucial regulatory role.

When is this test recommended?

It is suggested that:

When the preliminary tests reveal the presence of leukaemia or lymphoma symptoms, a kind needs to be identified.

Identify autoimmune disorders caused by discrepancies in the CD19 identification to track the effectiveness of treatment for those diseases.

Test applications for CD20:

• Using CD19 and CD20 markers to confirm the total absence of B cells in suspected primary humoral immunodeficiencies, patients with suspected CD20 deficiency are assessed for the disease (humoral immunodeficiency).
• In any clinical setting, including treating acute humoral rejection in recipients of positive crossmatch renal transplants, autoimmune diseases like rheumatoid arthritis and systemic lupus erythematosus, among others, quantitatively measuring therapeutic B-cell depletion (absolute counts of cells/MCL).

It measures what exactly?

• The test for CD19 flow cytometry:
  • The biomarker CD19 can identify follicular dendritic cells and healthy and malignant B cells.
  • In modulating both B cell receptor-dependent and independent signalling, CD19 plays a crucial role in determining the intrinsic B cell signalling thresholds.
• Using flow cytometry, these antigens are quantified and recognised in this test, aiding in the detection of B-cell lymphoma.

How often should you get a CD19 Flow Cytometry test done?

Your doctor orders the CD19 Flow Cytometry test following a thorough health evaluation.

What are the CD19 Flow Cytometry test's average results?

Absolute CD19: 99–527/uL, 6–22%

What is flow cytometry?

It is one of the most recommended tests since it helps with management. The exam makes use of a laser.

Throughout this examination, the laser measures the cells.

The cancer cells show a distinct kind of light.

Suitable examples include:

• bones' marrow
• bodily tissues

Procedure:

• A dye is added to the cells.
• They are then transferred to a fluid.

Cancer cells produce a variety of light colours.

• Utilised to find the following:
  • Male T-cell lymphoma
  • many myelomas