Chimerism Pre- Engraftment Test Cost & Procedure

This test is used in patients who are about to undergo a transplant. Before the transplant, the blood or bone marrow is to be tested. If both donor cells and chimerism are seen: it denotes transport success.

What is Chimerism Split Cell Analysis

It is one of the most powerful methods to check the improvement in hematopoietic stem cell transplantation. This is done by investigating the recipient's blood samples in various malignant and non-malignant hematologic diseases.

What is malignancy?

Cancer can expand to various parts of the body. When cancer starts at one organ and slowly migrates to other organs, this condition is known as malignancy.

The hematological disorders diagnosed by this test are

• Lymphoma
• Myeloma
• Leukemia

Leukemia:

Leukos: "White"

Blood: "Haima"

Cause of leukemia

When the blood cells start developing abnormally, it causes leukemia. Variants of leukemia: It can be acute or chronic:

• Lymphocytic Leukemia
• myeloid Leukemia

Symptoms seen are:

• Fatigue
• Fever
• Loss of weight
• Splenomegaly
• Abdominal pain
• Bone pain
• Easy bleeding
• Fullness below ribs
• Night sweats
• Loss of appetite

It is a fatal disorder.

Risk Factors:

• Males
• Old age
• Radiation exposure

What is Multiple Myeloma?

It destroys the plasma cells. In this condition, the healthy cells become altered and affect the body's various organs.

Symptoms:

• Weakness
• Fatigue
• Nausea
• Vomiting
• Loss of weight
• Fever
• Bruising

What is Lymphoma?

It is lymphatic system cancer that helps to fight against infections. The lymphatic system includes :

• Lymph nodes
• Bone marrow
• Spleen
• Thymus gland

Types of lymphoma:

• Non-Hodgkin's Lymphoma
• Hodgkin's Lymphoma

Symptoms

• Fever
• Itchy skin
• Breathlessness
• Loss of weight
• Armpit groin
• Swollen lymph

Why is this recommended?

It aids in detecting the lineage of the hematopoietic cells in stem cell transplantation.

Any special requirement

No special provision is needed.

The procedure of this test

• A bone marrow sample or a blood sample can be advised.