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FISH (fluorescence in situ hybridization) testing is commonly used in the diagnosis and prognosis of chronic lymphocytic leukemia (CLL).
In CLL, FISH is used to detect specific genetic abnormalities, such as deletions or rearrangements of chromosomes, that may affect the prognosis of the disease. The most common genetic abnormalities detected by FISH in CLL are deletions in chromosomes 13q, 11q, and 17p, and trisomy 12.
The prognosis of CLL can vary depending on various factors, including age, stage of the disease, the presence of certain genetic abnormalities, and overall health status. In general, CLL patients with a normal FISH result or with 13q deletion have a better prognosis than those with other genetic abnormalities, such as 17p deletion or 11q deletion.
Patients with 17p deletion have a particularly poor prognosis, as this genetic abnormality is associated with resistance to standard CLL treatments, such as chemotherapy and immunotherapy. On the other hand, patients with 13q deletion generally have a better response to treatment and longer overall survival.
A FISH test detects specific changes in genes or chromosomes in chronic lymphocytic leukemia (CLL) cells.
It is recommended for patients with genetic abnormalities such as deletion of chromosomes 17q and 11 q.
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The cost of Chronic Lymphocytic Leukaemia Prognosis by FISH near me in Delhi ranges from INR 10,000 to INR 42,000
| Test Type | Chronic Lymphocytic Leukaemia Prognosis By FISH |
| Includes | Chronic Lymphocytic Leukaemia Prognosis By FISH (Hematology) |
| Preparation | |
| Reporting | Within 24 hours* |
| Test Price |
₹ 11700
|
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