Chronic Myeloid Leukemia (CML) Comboquest 1 Test Cost & Procedure

CML (Chronic Myeloid Leukemia) is a type of blood cancer that affects white blood cells. Combo quest 1 is a genetic test that can be used to diagnose and monitor CML.

Combo quest 1 is a FISH and Real-time polymerase chain reaction (RT-PCR) based test that detects the BCR-ABL1 fusion gene, which is characteristic of CML. The BCR-ABL1 fusion gene is created when a piece of chromosome 9, which contains the ABL1 gene, fuses with a piece of chromosome 22, which contains the BCR gene. This fusion gene produces a protein that is involved in the development of CML.

Why is CML Comoboquest 1 Done?

The Comboquest 1 test uses FISH analysis and RT-PCR to amplify and detect the BCR-ABL1 fusion gene in a patient's blood or bone marrow sample. The test can detect the fusion gene at a sensitivity of 0.01%, which means it can detect even very low levels of the fusion gene in the sample.

In addition to diagnosing CML, the Comboquest 1 test can also be used to monitor the response to treatment. After treatment, the level of the BCR-ABL1 fusion gene in the patient's blood or bone marrow sample should decrease. The Comboquest 1 test can detect changes in the level of the fusion gene over time, allowing doctors to monitor the patient's response to treatment and adjust the treatment plan as needed.

Sample Type Required

CML Comboquest 1  detects the BCR-ABL1 fusion gene in a patient's blood or bone marrow sample. The test can be used to diagnose CML and monitor the response to treatment.

Cost of CML Comboquest 1

The cost of CML Comboquest 1 near me in Delhi ranges from INR 9000 to INR 15000