Chronic Myeloid Leukemia (CML) Comboquest 2 Test Cost & Procedure

Chronic myelogenous leukemia (CML) is bone marrow cancer that causes an increased number of white blood cells in the blood. The problem of CML usually affects adults and causes symptoms such as bone pain, fever, bleeding, pain below the ribs, night sweats, etc.

CML Comboquest II is the methodology to diagnose Chronic myelogenous leukemia (CML). This comboquest involves two testing methodologies Conventional karyotyping and RT-PCR.

Comprehensive BCR/ABL analysis by conventional karyotyping

Conventional karyotyping is a type of chromosomal analysis that examines the number, size, and shape of chromosomes in a cell. It is useful for detecting large structural chromosomal abnormalities, such as translocations, deletions, and duplications.

 In the context of BCR/ABL analysis, conventional karyotyping can be used to detect the Philadelphia chromosome, a translocation between chromosomes 9 and 22 that results in the BCR/ABL fusion gene. This fusion gene is commonly associated with chronic myeloid leukemia (CML) and some cases of acute lymphoblastic leukemia (ALL).

 RT-qPCR is a technique used to measure the levels of cancer-specific RNA molecules in a patient's blood or bone marrow sample. This technique can be used to detect and quantify MRD, which is an important indicator of the effectiveness of cancer treatment. The baseline value is the level of cancer-specific RNA molecules in the patient's sample before treatment and is used as a reference point for measuring MRD levels during and after treatment.

Sample Type Required

Blood sample

Or

Bone Marrow

Preparation

Provide the complete clinical history to a doctor before the testing procedure

Cost of CML Comboquest II

The cost of CML Comboquest II near me in Delhi ranges from INR 9000 to INR 20000