Coombs Test Direct (Gel Technology) Test Cost & Procedure

The Coombs Test Direct, also known as Direct Antiglobulin Test (DAT), is a laboratory test that detects the presence of antibodies attached to the surface of red blood cells. This test is used to diagnose and monitor autoimmune hemolytic anemia (AIHA), a condition in which the body's immune system produces antibodies that attack its red blood cells. The test can also be used to detect antibodies produced in response to blood transfusion reactions and to screen for hemolytic disease in the newborn.

Why is Coombs Test Direct (Gel Technology) Done?

There are several reasons why the test may be done:

• To diagnose autoimmune hemolytic anemia (AIHA): AIHA is a condition in which the immune system produces antibodies that attack the body's red blood cells, causing hemolysis (destruction of red blood cells). The Direct Coombs Test can detect the presence of these antibodies on the surface of red blood cells.
• To monitor treatment of AIHA: The Direct Coombs Test may be done to monitor the effectiveness of treatment for AIHA, such as corticosteroids or other immunosuppressive therapies.
• To investigate a transfusion reaction: The test may be done to investigate a transfusion reaction, which can occur when a patient's immune system reacts to donor blood that is not compatible with their own.
• To screen for hemolytic disease of the newborn (HDN): The Direct Coombs Test may be done during pregnancy to screen for HDN, a condition in which the mother's antibodies attack the baby's red blood cells.

How is Coombs Test Direct (Gel Technology) Done?

The coombs test directly involves the mixing of a patient’s blood in a small amount with anti-human globulin (AHG) reagent in a test tube. If the red blood cells of the patients have antibodies attached to their surface, the anti-human globulin (AHG) reagent will bind to these antibodies, causing the red blood cells to clump together, which is visible as agglutination.

Cost of Coombs Test Direct (Gel Technology)

The cost of Coombs Test Direct (Gel Technology) near me in Delhi starts from INR 680