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EGFR stands for Epidermal Growth Factor Receptor.
EGFR is a trans-membrane glyco-protein. The intracellular domain of EGFR protein is tyrosine kinase domain that regulates signaling pathways for cell growth, cell survival, cell division, and cell death.
Mutations in EGFR gene result in uncontrolled cell growth due to excessive or sustained growth signals.
Mutations in EGFR are associated with types of lung cancer such as Lung Adenocarcinoma, which is the most common type of Non-Small Cell Lung Cancer (NSCLC).
Following samples are collected for EGFR quantitative PCR:
Following is the procedure for EGFR mutation PCR:
Appointment –
Book an appointment beforehand, to avoid waiting and confusion.
Sample collected –
Blood sample is collected. FREE HOME SAMPLE COLLECTION AVAILABLE.
Procedure for blood sample collection –
Real Time PCR –
32 different mutations in EGFR can be detected simultaneously in the laboratory using a Real Time PCR machine, operated by a skilled technician.
Report –
There is no specific preparation required for EGFR mutation PCR. Let your healthcare professional know about the following:
The cost of this test varies from lab to lab. The best place to get this test done is Ganesh Diagnostic and Imaging Centre. The cost is reasonable and you can also avail FLAT 50% discount.
Test Type | EGFR Mutation Detection |
Includes | a |
Preparation | There is no specific preparation required for EGFR mutation PCR. Let your healthcare professional know about the following:
|
Reporting | Within 24 hours of sample collection. |
Test Price |
₹ 6250
|
Lung cancer is broadly categorized into:
The Non-Small Cell Lung Cancer (NSCLC) accounts for majority of lung cancer cases. EGFR mutation is generally seen in Lung Adenocarcinoma, which is a type of NSCLC.
There is no risk associated with non-invasive sample collection such as blood sample. In case, biopsy of tissue is required, your doctor will let you know about the procedure.
Following people are at higher risk of developing spontaneous somatic mutations in EGFR gene:
It means that you have a spontaneous mutation in EGFR gene. This is an indication towards uncontrolled cell growth and division in the body, most probably in lungs. The mutation occurs in somatic cells.
Following symptoms of EGFR positive lung cancer should not be ignored:
Early check ups are always better than delayed ones. Safety, precaution & care is depicted from the several health checkups. Here, we present simple & comprehensive health packages for any kind of testing to ensure the early prescribed treatment to safeguard your health.