EGFR Mutation Analysis for Stratifying Patients with NSCLC Test Cost & Procedure

This analysis seeks to identify any EGFR gene mutations linked to non-small cell lung cancer (NSCLC). An important platform for the identification of the genes responsible for NSCLC is the Amplification Refractory Mutation System (ARMS), an enhanced version of the polymerase chain reaction (PCR).

It often advances and metastasizes more gradually than small-cell lung cancer. Adenocarcinoma, squamous cell carcinoma (SCC), and giant cell carcinoma are the three subtypes of NSCLC.

Since stage greatly influences the type of treatment chosen, patients with NSCLC undergo a thorough staging workup to determine the degree of the disease.

Why is this test recommended?

Non-Small Cell Lung Cancer patient's tumor tissue is examined in this procedure. Based on the results, the patient will receive treatment for lung cancer. The blood plasma employed in this test serves as the analytical medium instead of tumor tissue because acquiring tumor tissue through a biopsy is painful for the patient. One of the leading causes of cancer-related mortality in both men and women is lung cancer.

Cancer of the lung symptoms:

• Coughing
• chest pain

respiration difficulty:

• Wheezing.
• having a bloody cough
• Being worn out
• Weight loss

What do you mean by EGFR?

It is a receptor protein that is transmembrane. The extracellular protein ligands belonging to the EGF family are receptive to the EGFR protein.

Results interpretation

• If a patient's lung cancer possesses a sensitizing EGFR mutation, they may be able to successfully treat it with an EGFR-targeted tyrosine kinase inhibitor (TKI).
• The presence of an EGFR mutation can occasionally be used to predict cancer's resistance to TKI treatment.
• Oncologists and pathologists assist in interpreting the specific relevance of the precise.

Method of testing:

The process consists of the following steps:

• Tumour samples' DNA is isolated.
• The kit's reagents are used to create a PCR setup.
• Utilizing a real-time PCR apparatus for amplification and detection