Epstein-Barr Virus Antibody to Nuclear Antigen, IgG

Benefit in the determination of EBV disease (infectious mononucleosis). EBV nuclear antigen (EBNA) IgG antibodies do not come across during the acute stage of infection but seem around 2-4 months after the initial clinical exhibition and generally exist for life. The existence of EBNA IgG antibodies in healthy people generally demonstrates past immunological disclosure of EBV; however, false positive results can happen.

Also, about 5-10% of individuals contaminated with EBV never evolve EBNA IgG antibodies. Because of the complex connection that lives between the EBV virus/host reaction and clinical manifestation, the search for EBV antibody customs may help in the diagnosis of EBV infection.

Process

Immunoassay (IA)

Reference Range

U/mL   Variation

Less than <18.00 Negative

18.00-21.99 Equivocal

Greater than>21.99 Positive

Optional Name

Epstein Barr virus Nuclear Antigen Antibody, Epstein Barr virus Past Infection, EBV NA

EBV nuclear antigen (EBNA)

Antibody to EBNA, specified by the standard immunofluorescent test, is not noticed in the acute stage of EBV infection but gradually emerges two to four months after the outset of signs and exists for the remainder of a person’s life.

How is the Test Performed?

The EBV test is generally a blood test. During the test, blood is taken at your hospital. Blood is taken from a vein, normally on the top of your elbow. The method comprises the following steps:

The site is tidied up with an antiseptic solution.

An elastic band is bound around your upper arm to create your vein swell with blood.

A needle is carefully deep down into your vein to take blood in a tube.

The band is peeled off from your arm.

The blood sample is transported to a lab for examination.

Interpretation of EBV Antibody Tests

EBV antibody tests are not generally required to determine infectious mononucleosis. However, precise antibody tests may be required to determine the reason for infection in people who do not have an ordinary case of infectious mononucleosis or have additional infections that can be provoked by EBV infection.

Epstein-Barr Nuclear Antigen (EBNA) antibody

Does not mainly diagnose until the acute disease has settled; it formulates about 2 to 4 months after the beginning of the infection and then persists for life.