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Glucose-6-phosphate dehydrogenase (G6PD) is an enzyme that plays an essential role in protecting red blood cells from damage by reactive oxygen species. G6PD deficiency is a genetic condition that affects the activity of this enzyme and can lead to hemolytic anemia in response to certain triggers such as certain medications, infections, or foods.
A qualitative test for G6PD activity involves the use of a chemical called NADPH (nicotinamide adenine dinucleotide phosphate) that is produced when G6PD catalyzes the conversion of glucose-6-phosphate to 6-phosphogluconate.
In this test, a small amount of blood is collected and mixed with a solution containing glucose-6-phosphate and NADP. If G6PD is present and active in the sample, it will catalyze the conversion of glucose-6-phosphate to 6-phosphogluconate, producing NADPH in the process. The presence of NADPH is detected by a color change or other means, indicating that G6PD activity is normal.
If G6PD is absent or deficient in the sample, there will be no or very little production of NADPH, and there will be no color change or other indication of G6PD activity. This indicates a G6PD deficiency, which may require further testing and medical management to prevent hemolytic anemia.
The cost of G6PD Activity (Qualitative) near me in Delhi ranges from INR 300 to INR 1500.
Test Type | G6PD Activity Qualitative |
Includes | G6PD Activity (Qualitative) Test (Hematology) |
Preparation | |
Reporting | Within 24 hours* |
Test Price |
₹ 575
|
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