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GAD65 IgG antibody is an autoantibody that is produced by the immune system of some individuals who have certain autoimmune disorders, particularly type 1 diabetes and stiff person syndrome (SPS). GAD65 stands for glutamic acid decarboxylase 65, which is an enzyme that is involved in the synthesis of the neurotransmitter gamma-aminobutyric acid (GABA) in the brain and pancreas.
In individuals with type 1 diabetes, the GAD65 IgG antibody attacks and destroys the beta cells in the pancreas that produce insulin, leading to insulin deficiency and hyperglycaemia. In people with SPS, the GAD65 IgG antibody attacks and damages the neurons that control muscle movement, causing muscle stiffness and spasms.
The GAD65 IgG antibody test is a blood test that measures the levels of GAD65 IgG antibodies in the blood. The test is used to diagnose autoimmune disorders such as type 1 diabetes and stiff person syndrome (SPS), which are associated with the presence of these antibodies in the blood.
The test is typically ordered when a person presents with symptoms that suggest type 1 diabetes or SPS, such as
The test may also be ordered as a follow-up to other tests that suggest an autoimmune disorder.
Blood sample
The cost of GAD65 IgG Antibody Test near me in Delhi ranges from INR 3500 to INR 15000.
Test Type | GAD65 IgG Antibody |
Includes | GAD65 IgG Antibody Test (Diabetology) |
Preparation | |
Reporting | Within 24 hours* |
Test Price |
₹ 4350
|
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