Histopathology Direct Immunofluorescence Skin Biopsy, IgG Test and Its Price in India

What is a biopsy?

It is a diagnostic procedure in which a portion of tissue of the diseased organ is taken and examined under a microscope.

Immunofluorescence Test

This test is used in labs to detect various diseases of the skin, heart,  kidney, and other organs.

In this test, a unique bar pairing occurs between antigen and antibody to identify the proteins in the blood sample.

It is a microscopic method used to detect diseases.

Types of immunofluorescence

• Direct immunofluorescence
• Indirect immunofluorescence

Direct Immunofluorescence

This type of immunofluorescence uses a single antibody, which is linked to a fluorophore. This antibody identifies the marked molecule and binds to it. The microscope identifies this bonded molecule.

The diseases which are diagnosed with this test are.

Bullous pemphigoid

• This is an autoimmune disorder.
• It most commonly affects older adults.
• The abdomen and legs are mostly affected.

Bullous pemphigoid

• It is an inflammatory disease
• Inflammatory cells are seen
• Also, it is more severe in the initial days.

Bullous pemphigoid

• It helps in the preservation of edema.

Bullous pemphigoid

It is an autoimmune disease caused by skin antibodies.

Epidermolysis Bullosa Acquisita

• It is seen in mid-life
• Trauma can cause this
• Limbs are mostly affected

Epidermolysis Bullosa

It is a non-inflammatory disease with blister formations.

• It is inherited.

Dermatitis Herpetiformis

• Related coeliac disease
• This can happen at any age
• It affects the back and arms of the patient

What is lupus systemic erythematosus?

The body's immune system is affected, an inherited disease affecting older adults.

Bullous Diseases:

Itchy rashes are seen in this disease and affect adults.

Vasculitis

When the body's blood vessels get inflamed, this condition is known as Vasculitis. Vasculitis can affect all the blood vessels starting from tiny blood vessels to large blood vessels.

When the blood vessels get inflamed, their blood becomes weak and stretches in size.