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HLA-A is a member of the HLA class I heavy chain parallels. This class I element is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). Class, I elements play a major portion in the immune system by illustrating peptides emanating from the endoplasmic reticulum lumen. They are articulated in nearly all cell linings. The heavy chain is roughly 45 kDa and its allele comprises 8 exons.
Exon 1 codes the leader peptide, exons 2 and 3 code the alpha1 and alpha2 parts, which are both attached to the peptide, exon 4 codes the alpha3 domain, exon 5 codes the transmembrane part, and exons 6 and 7 code the cytoplasmic end. Indexing for these polymorphisms is mainly accomplished for bone marrow and renal transplantation.
HLA B27 flow cytometry examination is conducted on a specimen of blood to estimate the grade of HLA B27 antigen in your blood. It is conducted to discover whether these are existing the blood:
Furthermore, it is executed during and after the therapy of Autoimmune Diseases.
No particular preparation is required for the HLA B27 Flow Cytometry examination. You don’t require to reverse your diet for this examination. You can both eat and drink usually. Notify your physician if you are on any prescriptions or have any earlier medical ailments or any kind of allergies before going for HLA B27 Flow Cytometry Blood Examination. Your physician will evaluate your history and ailment and provide precise teachings for going for an examination.
The ordinary outcome for the HLA B27 Flow Cytometry examination for HLA B27 Ag is Commonly unfavorable for ordinary beneficial human beings. A favorable outcome will show consistency with SpA, acute anterior uveitis, or juvenile idiopathic arthritis. Nonetheless, the populace who experimented favorably with HLA-B27 optimistically will not necessarily retain an associated ailment. A negative HLA-B27 impact does not facilitate the ailments related to HLA-B27; the allele might not always look after individuals with these diseases.
Flow cytometry technique is utilized. Foremost, the lab attendant will purify your arm with an antiseptic. To create anxiety and reason your veins to bulge with blood cells, a crew will be pertained to around your arm. A syringe will be stuck in one of your veins to attract a little specimen of blood.
A reasonable quantity of blood will be compiled and the syringe will be withdrawn and a tiny dressing will be seated on your arm where the syringe was stuck in. You’re instructed to conserve some anxiety in the area as it lessens blood discharge.
Test Type | HLA B27 Flow cytometry Method |
Includes | HLA B27 Flow Cytometry Method Test (Rheumatology) |
Preparation | |
Reporting | Within 24 hours* |
Test Price |
₹ 1700
|
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