HLA Typing (A, B, C, DR & DQ) Test Cost & Procedure

An output of high-resolution typing is a group of genes that specify and code for the same protein series for the peptide binding region of an HLA molecule and that prohibits genes that are not designated as cell surface proteins. HLA typing at less than 4 numbers in bone marrow transplants is modified in this investigation.

The HLA allele's gene interpretation can be ascertained using DNA sequencing, which is a significant operation. Class I (HLA-A, -B, -C) and class II (HLA-DR, -DQ, and -DP) alleles' highly polymorphic exons are typically the focus of sequencing. These exons encode the antigen recognition region of the HLA molecule, which binds peptides and connects with the T cell antigen receptor and immunoglobulin-like receptors on natural assassin cells (KIR).

How Is the Test Performed?

You will need to put on a tissue samples in order to take the HLA typing test. Typically, the specimen is obtained from a blood sample drawn from an arm vein or from a swab that moves on the inside of your cheek.

There is no preparation for the exam that you must complete. Once carried, your specimen is sent to a specific lab to be examined.

How does matching occur?

You must donate blood samples, or you must deliver the cheek-swab sample, along with any potential donors.

Your HLA class is ascertained through laboratory testing on cheek or blood samples.

To determine whether there is a match, your HLA class will be roughly matched to potential donors. Which donor is a reasonable HLA match for you will be determined by your doctor.

Summary

Human leukocyte antigen (HLA) typing is used to identify potential precise matches for patients who require transplants.

People who need solid organs or stem cells for a transplant function normally when they "match up" with donors in particular ways. Their HLA type is one method, which looks at immune system genes and proteins.

In order to determine whether the recipient's body is rejecting the organ, HLA typing can also be used after the transplant has been completed. This could be a halt if anything went antagonist with the transplant.