IHC - Cluster of Differentiation 23 (CD23) Test Cost & Procedure

It is crucial for controlling IgE levels. CD23 is a C-type lectin, not antibody-like receptor-like many others. It is present on platelets, eosinophils, activated macrophages, mature B cells, and follicular dendritic cells.

The CD23 Test is what?

In the control of antibody feedback, CD23 plays a part. Differentiating chronic lymphocytic leukemia from other lymphocytic leukaemias is a cell surface protein. IgE (immunoglobulin E) antibodies specific for a given antigen can capture blood-borne antigens, and CD23 is involved in the control of IgE. MCL, or mantle cell lymphoma, expresses CD23. However, it is harmful in MCL and positive in small lymphocytic lymphoma (SLL). Low-grade B-cell lymphomas can be classified in diagnostic ways using antibodies to CD23.

Preparation for the CD23 Test

Data is gathered through blood samples to identify patients with CD23 negative, which may be a symptom of Mantle cell lymphoma. Wear half-sleeves or loose-fitting clothing so you can roll up the sleeves. Observe the instructions provided at the testing location. If you need to act quickly, information will be provided. CD23

Test Applications

Mantle cell leukaemia (MCL), a more aggressive illness with a poor response to conventional therapy, is suggested by CD23 negative in patients with CD19/CD5 levels.

How to Perform the CD23 Test?

• Western blotting is a standard analytical method for separating and identifying proteins in scientific studies.
• Before the test, the following step is necessary: Utilizing an alcohol pad, it is cleaned.
• The vein is used instead of the arm for the needle insertion.
• Division by size, Moving to a stable support and employing the proper primary and secondary antibodies to mark the target protein visually