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It is possible to employ MUM1 as a marker for lymphohematopoietic neoplasms developing from activated T cells and late plasma cell-driven stages of B cell development because of the multiple myeloma oncogene's expression in these cells.
MUM1 is expressed in extraosseous plasmacytomas and plasma cell myeloma. Melanomas have been found to express MUM-1 among non-hematolymphoid neoplasms.
MUM1 is a gene that is used for proteins. Its name, Multiple Myeloma Oncogene-1, or MUM-1, is how it is expressed. Melanoma is one condition that MUM1 affects many people. The MUM1 gene's coding demonstrates that it is one of the factors contributing to DNA damage and chromosomal abnormalities. Immunohistochemistry and tissue microarrays are used to perform the MUM 1 protein test.
The process is known as immunohistochemical staining (IHC). Consequently, the Mum1 gene encodes the 50 kDa MUM 1 protein. Antigen-stimulated B cells that can develop into plasma cells are the source of MUM 1 expression.
A patient must follow the doctors' instructions, nevertheless. He might be instructed to skip his existing medications or to fast for the duration of the test.
Determine if there are any malignancy-related symptoms. It facilitates additional research into hematolymphoid neoplasm. The test enables medical professionals to recognise melanomas and begin appropriate treatment.
Test Type | IHC-Multiple Myeloma Oncogene 1 (MUM1) |
Includes | IHC - Multiple Myeloma Oncogene 1 (MUM1) (Pathology) |
Preparation | |
Reporting | Within 24 hours* |
Test Price |
₹ 1325
|
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