Progesterone Receptor (PR) Test - Book at Affordable Cost

What is Progesterone Receptor?

The Progesterone Receptor is a nuclear receptor. It gets activated by the progesterone hormone.

PR gets encoded by the progesterone hormone. In the human beings, this PR gene is encoded by the single PGR gene which is seen to reside on the chromosome 11q22

It is seen that, progesterone hormone is necessary for inducing activation of your progesterone receptors. In this case, when there is no binding hormone present, your carboxyl terminal would inhibit transcription.

In females, we come across PRA and PRB are detected in the nuclei of the reproductive systems of women.

These receptors are further found in the following organs: Small Intestine, Liver, Kidney, Urinary Bladder, Skin and Adrenal Gland.

Why is Progesterone Receptor Test Done?

Progesterone Receptor Test is used to diagnose certain health ailments. For example- Breast Cancer.

As Breast Cancer is known to be sensitive to progesterone, cells also have receptors that would allow them to use this particular hormone for its growth. The treatment of breast cancer with the endocrine therapy is seen to block your growth of cancer cells.

Most often than not, the Progesterone Receptor (PR) is used in combination with Estrogen Receptor, (ER). These will determine which cancers are positive or either one or both receptors.

Even if the 1% of your PR receptor, if the value has a positive PR, and it is detected, it is utmost essential that any individual who is advised an immediate consult from their doctor for any proper treatment.

If addressed by the healthcare professional, to find out the cancerous parts.

Note: It is also very important that testing would be done in the laboratory followed by necessary and any specific requirements along with following the standard protocol of this PR testing.

How to Prepare for the Test?

This is mostly done in form of a blood test, so not much preparation is needed in that aspect.

The PR can also involve Biopsy Procedures. In this regard, these 3 types of breast biopsies may be needed:

• FNAC: Fine Needle aspiration Biopsy using a thin needle, receiving the breast cells or the fluids
• Core Needle Biopsy: Use a large needle to remove this sample
• Surgical Biopsy: Will be an outpatient procedure, which would be quite minor in nature.

In case of Biopsy, when anesthesia is required, you are requested to fast (not eat or drink) for at least 4-6 hours before the test.

In case, if one would get a sedative or the general anesthesia, is sure that someone to drive the individual home soon.

Test Procedure

The cancerous tumours of your breast are requiring a proper and standard diagnosis and treatment. Importance of accurate testing is needed successful treatment and any proper medication the testing should follow a proper protocol.

In case of Blood Test, 2ml of your sample would be needed.

Your PR or the Progesterone receptors are also called as the immunohistochemistry (IHC) which needs to be done by detecting the Progesterone Receptor (PR) presence from testing the tissues which would be collected as samples in the form of biopsy.

In most of your cases, the treatment might require removal of the tumor from the breast or the whole breast.

After the tests

• Even though there no specific risks to this test procedure.
• If the site (biopsy) can get infected, antibiotics are further needed.
• However, a minor discomfort may be experienced at the injection site if Blood Specimen is taken.

Result Interpretation

The Normal Values for PR or the Progesterone Receptor Test is as follows:

 The Progesterone Receptor for all the females in all the different age groups should have a value of negative

Cost of Progesterone Receptor Tests in Delhi

The Progesterone Receptor Tests varies INR 1500 to INR 2500 by region and facility. So constantly get tested at trustworthy diagnostic centers like Ganesh Diagnostic. It is staffed by trained and experienced professionals to assure patient and visitor safety.

So get your Progesterone Receptor Test done your nearest Ganesh Diagnostic Center.