Leukemia Genetic Profile- Any 6 Markers PCR Qualitative Test Cost & Procedure

This test identifies the risks of AML(Acute myeloid leukemia)/ ALL(Acute Lymphoid leukemia).

The markers used for this test are:

1. MLL-AF4 -
   • Used for the detection of AML
2. MLL-ENL -
   • Mixed lineage leukemia-Eight nineteen leukemia
3. T(12;21)
4. T(1;19)
5. MLLAF9
6. NPM1
7. BCR-ABL
8. PML-TARA
9. INV16

Leukemia:

Leukos: "White"

Blood: "Haima"

This is a condition in which the DNA present in the cells of your bone marrow mutates and cannot function appropriately.

It is a blood cancer with frequent growth of blood cells.

It cannot be diagnosed by X-ray or CT scan as it does not appear as a mass.

Cause of leukemia:

The blood cells start leukemia when they abnormally start growing. The blood cells present are :

• Platelets
• White blood cells
• Stem cells
• Red blood cells

Types of Leukemia:

1. Acute Lymphocytic Leukemia:
   • Mainly seen in infants
2. Acute myeloid Leukemia:
   • Mostly seen in adults
3. Chronic Lymphocytic Leukemia:
   • Mainly seen in adults who are more than 65 years.
4. Chronic myeloid Leukemia:
   • Rarely seen in children.
   • No symptoms were seen.

Classification based on the speed of progression of the disease:

1. Chronic LeukemiaBothas both mature and immature blood cell involvement.
   • More often seen in adults.
   • Shows no symptoms for a long Time.
   • Slowly progresses
2. Acute Leukemia:
   • The abnormal cells divide very rapidly.
   • Shows symptoms of weakness within a few days.
   • Fatal disease
   • Fast-progressing disease.
   • Mainly seen in Children

Classification based on cell type:

• Lymphocytic Leukaemia
• Myeloid leukemia

Acute Myeloid Leukaemia (AML):

This is a blood cancer and affects the bone marrow too.

It is said to be perceptive as it has shown a fast progression to make immature cells.

The significant symptoms seen are:

• Fever
• swollen lymph nodes
• Bone pain
• Bruising
• Gum bleeding
• Recurrent infections
• Nausea
• Dark skin
• Weakness
• Difficulty in breathing

Acute Lymphocytic Leukaemia (ALL):

This is a blood cancer and affects the bone marrow too.

It is said to be cute and has shown fast progression to make immature cells.

It is a type of leukemia seen mainly in children.