LiquiCORE PIK3CA High Resolution Test Cost & Procedure

The PIK3CA gene contains the information needed to produce the p110 alpha (p110) protein. P110 serves a variety of purposes in the body, including:

• cell division and growth
• protein production via cell movement
• material flow within cells, cell survival
• Some hormones may be regulated by PI3K signal signaling.

This procedure can be interfered with by a PIK3CA gene mutation, leading to uncontrolled cell division and replication. Up to 4 0% of breast cancers with human epidermal growth factor receptor 2 (HER2)-negative, ER-positive tumours  PIK3CA mutations.

If it is discovered that your tumour tumor PIK3CA mutation, emerging therapies that target the PIK3CA gene mutation directly may be beneficial.

• Breast cancer with metastatic PIK3CA mutation
• The term metastatic breast cancer (MBC), commonly referred to as stage 4 or advanced breast cancer, refers to cancer that has spread from the breast tissue to organs like the liver, lungs, or brain.

Advanced breast cancer has a decreased chance of survival, but with the correct care, both length and quality of life can be increased.

However, individuals with early-stage breast cancer don't frequently undergo testing for a PIK3CA mutation. Clinical guidelines recommend testing for PIK3CA mutations after a person has metastases from breast cancer.

Preparation

The patient should be informed in advance about the test's advantages and disadvantages as well as any related difficulties. It is important to remove all misconceptions patients may have regarding the test and sample collection process. Before the test and sample collection, clean surroundings, well-stained slides, and needles should be used. With a very neat and clean cotton cloth, wipe the margins of the sample extraction area and the discoloured area.

PIK3CA Test Applications:

The PKI3CA is one of the tests that give the patient a little amount of confidence in their sickness and its diagnosis. Normal cancer should be found early on in the course of its development.

How to perform the PIK3CA test?

• The best option is a broad needle with good compatibility for extraction.
• The specific tumour location/cancer-affected area should be located over the patient’s body with the help naked hand and should be cleaned with alcohol before piercing the afflicted portion for the sample extract.
• 10-15 ml of the serum must be withdrawn from the tumour ball to the needle and collected in a tidy tube which is then sent to the actual examination location.
• Make sure that no blood enters the sample while it is being taken from the patient's body.
• Once the sample has been taken, cover the area that has been punctured with linen or cotton to prevent blood from dripping there.