Macroprolactin Test - Book at Affordable Cost

Serum Macroprolactin : What is it?

A macroprolactin isoform with a prolonged clearance rate akin to immunoglobulins is often made up of a prolactin monomer and an IgG molecule. The immunological techniques used to detect prolactin are hampered by this isoform, despite the fact that it is not clinically reactive.

What does having High Macroprolactin mean?

A prolactinoma, a form of pituitary gland tumor, is frequently seen when prolactin levels are greater than normal.

Why do you need a macroprolactin test?

The purpose of this test is to investigate the reasons behind elevated blood prolactin levels. Its major function is to start and keep breast milk production going.

What causes elevated levels of Macroprolactin?

• Typical causes include
• Thyroid tumors (prolactinomas)
• Hypothyroidism (underactive thyroid) (underactive thyroid)
• Medications prescribed for high blood pressure, psychosis, and depression.
• Herbs, such as red clover, fennel seeds, and fenugreek.
• Discomfort in the chest wall (from surgical scars, shingles, or even a too-tight bra)

A Tumor, is Macroprolactin?

The most frequent kind of pituitary adenomas are prolactinomas. in size. In addition to complaints brought on by the tumor mass and compression of neurally nearby regions, these tumors frequently produce excessive amounts of prolactin, which in turn causes symptoms.

What signs or symptoms indicate elevated macroprolactin?

Menstrual irregularities or absence, infertility, menopausal symptoms (hot flashes and vaginal dryness), and, after a number of years, osteoporosis are all signs (thinning and weakening of the bones). Moreover, excess prolactin levels can result in breast milk leakage.

Can macroprolactin contribute to infertility?

15% to 20% of women who experience menstrual irregularities and 30% to 40% of infertile women have hyperprolactinemia, which can have a negative impact on fertility.

What role does Macroprolactin play in clinical practice?

Hence, screening all individuals with high sera PRL levels may be helpful to avoid pointless inquiries into the origin of hyperprolactinaemia.

What Prolactin concentration denotes a Tumor?

Less than 20 nanograms of prolactin per milliliter constitute a normal level. A prolactinoma is often detected when the prolactin level exceeds 150–200 nanograms per milliliter.

How serious is Macroprolactinoma?

Prolactin production by the pituitary gland is increased as a result of this malignancy. A prolactinoma primarily affects the levels of several sex hormones, specifically estrogen and testosterone. A prolactinoma does not pose a risk to life. Yet, it can lead to infertility, vision issues, and other issues.

What is the Macroprolactinoma Treatment?

In individuals with microprolactinomas and the majority of patients with macroprolactinomas, transsphenoidal pituitary adenomectomy is the surgical procedure of choice. Only patients with significant extrapituitary extension receive a transcranial approach.

Is having macroprolactin typical?

A small percentage of persons have macroprolactin, a biologically inert type of prolactin. In actuality, it is IgG bound to prolactin. Macroprolactin is significant because it can be mistaken for prolactin by various laboratory techniques, resulting in erroneously high prolactin results.

What is the Cost of Macroprolactin Test

The Macroprolactin Test cost varies by region and facility. So, constantly get tested at trustworthy diagnostic centers like Ganesh Diagnostic. It is staffed by trained and experienced professionals to assure patient and visitor safety.

The average price for this test is seen to differ from one center to another. The price range is said to be between INR 5000 to INR 2500 in Delhi.