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Megaloblastic anemias are a group of blood disorders characterized by the production of abnormally large and immature red blood cells, called megaloblasts, in the bone marrow. Megaloblastic anemias are typically caused by a deficiency in vitamin B12 or folic acid, which are essential for normal red blood cell production and DNA synthesis.
The most common causes of megaloblastic anemias are deficiencies in vitamin B12 or folic acid absorption, often due to inadequate dietary intake, malabsorption disorders, or other underlying medical conditions. These deficiencies can result in impaired DNA synthesis in red blood cell precursors, leading to megaloblasts with delayed maturation and enlarged size.
Common symptoms of megaloblastic anemias may include fatigue, weakness, pale skin, shortness of breath, and an enlarged spleen. Neurological symptoms such as tingling and numbness in the hands and feet, difficulty with balance and coordination, and mood changes may also occur in vitamin B12 deficiency.
Complete blood count | 175 | |
Reticulocyte count | 175 | |
Vitamin B12 | 525 | |
Methylmalonic acid (MMA) Quantitative, Serum | 1300 | |
Serum Homocysteine | 450 | |
Peripheral blood smear | 100 | |
Total Price | 2725 |
Megaloblastic anemias are typically manageable with appropriate treatment and monitoring, and prognosis depends on the underlying cause and response to treatment. It's important to consult a healthcare professional for proper diagnosis and management if you suspect you may have megaloblastic anemia or related symptoms.
Test Type | Megaloblastic Anemias |
Includes | Megaloblastic Anemias (Common Diseases) |
Preparation | |
Reporting | Within 24 hours* |
Test Price |
₹ 2725
|
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