MSH2 Gene Sequencing - Colorectal Cancer Test Cost & Procedure

What is MSH2 Gene Sequencing

To ascertain whether a person has MSH6 protein, the MSH6 Gene Sequencing test is employed. It is located in the patient's tumor tissue using immunohistochemistry. Only those with the condition and germline mutations will have it. This examination sees Lynch syndrome in individuals with colorectal cancer. Only 1% to 2% of people develop colorectal cancer due to mismatched MSH6 mutations. 40% of men and 20% of ladies, respectively, are at chance for colorectal cancer, according to an examination. Children only have a 50% chance of developing cancer even though mutations are handed down from parents.

Practice for MSH2 Gene Sequencing - Colorectal Cancer Examination

The MSH6 Gene Sequencing examination has no specific prerequisites that must be met before or after. It is always advisable to abide by your doctor's advice, even if your diet doesn't need any extra attention. Ahead of time, the patient should inform the doctor of any new diagnoses or treatments that they are receiving. If the patient has a history of allergies, it is advisable to inform the doctor and abide by their advice. The MSH6 Gene Sequencing test requires no additional preparation.

Advantages of MSH2 Gene Sequencing - Colorectal Cancer Examination

The MSH6 Gene Sequencing examination specifies whether an individual has colorectal cancer or Lynch syndrome. As a result, the following results are extrapolated from test results: An MSH6 test may not always reveal whether the patient has mutations. If the results do not match those from the clinical examination, then more testing must be done. When interpreting test results, it is important to take into account the clinical findings, family history, and laboratory data.

Method for MSH2 Gene Sequencing - Colorectal Cancer Examination:

The MSH6 Gene Sequencing test requires the collection of blood or DNA. This experiment will make use of bone marrow from an allogeneic donor. A full blood sample from the patient is taken for the test. They sanitize the area where blood must be extracted for the MSH6 test to prepare it. The examination of the vein requires blood to get blood extracted. After putting in the syringe, 3 Ml of blood is drawn and then transmitted into a clean tube. To assure that the blood is thoroughly mixed, invert the tube many times then provide the collected material to the lab for examination.

Conditions for Specimens

Specimen entire blood volume in a 5 ml EDTA tube.