Phospholipase A2 Receptor Antibody (pla2r) Qualitative Test Cost & Procedure

Antibodies that inform PLA2R1 can be utilized in several scientific applications, comprising Western Blot, Immunohistochemistry, Flow Cytometry, ELISA, and Immunocytochemistry. This Ab marks PLA2R1 in Human, Mouse, and Rat specimens. Our PLA2R1 polyclonal and monoclonal Ab are formulated in rabbits, mice, and Goats. These Ab have been ascertained by Relative expression to substantiate specificity to PLA2R1. Find the PLA2R1 Ab that matches your necessities. Choose from 1 of 9 PLA2R1 Ab, which has been certified in investigations with twenty-four pictures featured in our data aisle.

Qualitative Dosage of the Anti M-Type Phospholipase A2 Receptor Autoantibody:

Measures:

Serum anti-PLA2R antibodies were purified by indirect immunofluorescence examinations. If the results were negative, it stood followed a qualitative enzyme-linked immunosorbent assay quiz. Examinations were based on a commercial kit.

Methods:

We calculated keenness, carefulness, prognosis value, and likelihood percentage for examinations, using kidney biopsy conclusions performed at HMR as the gold criterion.

Results:

A total of one thousand six hundred nighty examinations were conducted among one thousand twenty-five patients during the analysis year. A slight ratio of these patients was followed at HMR. Patients tested at HMR and in the rest of Quebec had identical characteristics. Quiz facts were only identified for patients tested at HMR. Keenness and carefulness were, respectively, fifty-eight and hundred percent for the qualitative test, and seventy-one and hundred percent for the quantitative test. The combined net sensitivity was forty-two percent and the net specificity was hundred percent.

Limitations:

As the detailed examination was only feasible in the small percentage of patients clinically followed at HMR, there is a feasible selection bias. Another possibility of assignment bias was the emphasis on patients who were selected to have a kidney biopsy, presumably because of additional brutal infection, elevated probability of glomerulonephritis, or a second digit of comorbidities. Given the retrospective essence of this investigation, there was no organized kidney biopsy or serum PLA2R antibody testing conducted.

Phospholipase A2 Receptor Antibody (PLA2R) Qualitative Test Details

Short Description

This assay notices auto against phospholipase A2 receptors which are worthwhile in the appraisal of Primary membranous glomerulonephritis. MGN is a greatly frequent kidney ailment with nephrotic syndrome. Autoantibodies of type IgG against PLA2R are favorably explicit for the inspection of primary MGN and can be noticed in the serum of up to seventy to seventy-five percent of patients.

Examination Specifications:

• Specialty: Nephrologist
• Ingredients:
• Department Stores: Immunopathology
• Exporting Stability: Room Temperature: 6 hrs, cold storage:7 days, chilled: 14 days

PreTest Information

Overnight dieting is privileged.