PML-RARA Qualitative Test

Full forms:

PML – Promyelocytic Leukemia

RARA – Retinoic Acid Receptor Alpha

RT-PCR – Real Time Polymerase Chain Reaction

What is PML-RARA Qualitative test?

Promyelocytic Leukemia is a rare type of Acute Myeloid Leukemia (AML). 

It is caused due to translocation (mutation) between chromosome 17 and chromosome 15. This mutation is also referred as t (15, 17).

The Retinoic Acid Receptor Alpha (RARA) gene on chromosome 17 fuses with promoter region of the Promyelocytic (PML) gene on chromosome 15.

This fusion results in a gene called PML-RARA, the transcripts of PML-RARA are detected using RTPCR.

RTPCR showing qualitative presence of PML-RARA gene transcripts is called PML-RARA Qualitative test. 

What Samples Are Taken for This Test?

Following samples are generally collected for PML-RARA qualitative test:

• Whole blood sample
• Bone marrow sample 

How Pml-Rara Qualitative Test Is Performed Using RTPCR?

Following is the procedure for PML-RARA qualitative PCR test:

Appointment – 

Book an appointment beforehand, to avoid waiting and confusion. 

Sample collected – 

Blood sample is collected. FREE HOME SAMPLE COLLECTION AVAILABLE.

Procedure for blood sample collection –

• A phlebotomist will tie a tourniquet around your arm. 
• He will sanitize the area from where he is supposed to draw blood. 
• With the help of sterile needle, he will draw the required amount of blood sample.
• The sample will be transported to the lab for testing after labeling properly.

Real Time PCR – 

PML-RARA transcripts are detected in the laboratory using a Real Time PCR machine, operated by a skilled technician.

Report – 

• Report is available within 24 hours of sample collection.
• Report is available digitally.
• 100% accurate reports

How to Prepare for This Test?

There is no specific preparation required for PML-RARA qualitative Real Time PCR. Let your healthcare professional know about the following:

• Medical history
• Medication
• Family history

What Is the Cost of PML-RARA Qualitative Test?

The cost of this test varies from lab to lab. The best place to get this test done is Ganesh Diagnostic and Imaging Centre. The cost is reasonable and you can also avail FLAT 50% discount.