(q22_q12) gene rearrangement quantitative MRD.webp "pml rara t(15;17 )(q22;q12) gene rearrangement quantitative mrd monitor test")
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This test is exclusively performed to detect acute promyelocytic leukemia exposed to the translocation t(15;17)(q22q12).
This test is done to check the mutations of the chromosomes seen in patients with acute promyelocytic leukemia.
It is one type of acute myeloid leukemia. The bone marrow is responsible for producing hematopoietic and red blood cells. In promyelocytic leukemia, the bone is accumulated by the premature blood cells. This leads to the obstruction in the growth cycle of normal white and red blood cells.
Symptoms seen are.
It is usually seen in older adults.
Two genes are involved: PML and RARA.
The PML gene is seen on chromosome 15, whereas the RARA gene is located on chromosome 17. Mutations can affect genes at any moment of life. This is a somatic mutation.
It is recommended that any symptoms mentioned are seen in your profile test. Usually, it is advised after the complete blood count.
A dye named Oxazine is used. It differentiates the platelets as compared to the other cells of the blood. The fluorescence intensity achieved this.
It is a laser technique that helps in investigating the chemical and physical features of cells.
| Test Type | PML RARA T(15;17 )(q22;q12) Gene Rearrangement Quantitative MRD Monitor |
| Includes | PML RARA T(15;17 )(q22;q12) Gene Rearrangement Quantitative MRD Monitor Test (Hematology) |
| Preparation | |
| Reporting | Within 24 hours* |
| Test Price |
₹ 3380
|
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