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Breast carcinomas with EGFR gene amplification typically express more proteins. Only 2% of tumors in this study had apparent EGFR protein overexpression without gene amplification, and more research is required to determine its mechanism.
One of the primary and most important targets for innovative anticancer medicines is the epidermal growth factor receptor (EGFR).
Amplification of gene in breast cancer
Human epidermal growth factor receptor 2 (HER2) gene amplification at chromosome 17q (Chr17q) is seen in 15%–20% of breast cancer cases.
Epidermal growth factor receptor, a protein found in cells, promotes cell growth. There are various EGFR mutations.
An eGFR below 60 for three months or longer, or an eGFR above 60 with renal damage, both suggest chronic kidney disease (shown by high levels of albumin in the urine).To help plan your therapy, your medical team will try to determine the origin of your kidney illness and keep checking your kidney function.
The tumor marker eGFR
Introduction: In patients with advanced non-small cell lung cancer, associations between clinical outcomes and tumor markers associated with the epidermal growth factor receptor (EGFR) were examined.
Uncontrolled growth could develop into a tumor. Breast cancer that is HER2-positive has the propensity to spread (metastatic breast cancer) and grow more quickly (recur).
Two genes, BRCA1 and BRCA2, are crucial in the battle against cancer. These genes act as tumor suppressors.
A kid can inherit a dangerous BRCA1 or BRCA2 mutation from either parent.
Treatment of EGFR mutation
Although it is feasible, acute renal injuries have a higher chance of increasing GFR than chronic kidney disease. Most chronic illness patients may benefit from positive lifestyle changes to postpone the loss in kidney function.
| Test Type | FISH, EGFR Gene Amplification, Breast Cancer |
| Includes | FISH, EGFR Gene Amplification, Breast Cancer (Pathology Test) |
| Preparation | |
| Reporting | Within 24 hours* |
| Test Price |
₹ 6050
|
Early check ups are always better than delayed ones. Safety, precaution & care is depicted from the several health checkups. Here, we present simple & comprehensive health packages for any kind of testing to ensure the early prescribed treatment to safeguard your health.
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