Soluble Transferrin Receptor (sTfR), Serum Cost & Procedure

Soluble transferrin receptor conventionally directs to the cleaved extracellular part of transferrin receptor 1 that is discharged into the serum. This receptor is a protein dimer of two similar subunits, correlated together by two bonds of disulfide bonds. Its molecular weight is 190,000 Dalton.

Blood examination of the soluble transferrin receptor (sTfR) is manipulated as a calculation of usable iron level and the analysis of iron deficiency anemia.

What is being experimented on?

Soluble transferrin receptors (sTfR) are proteins located in the blood that can come to be boosted in the existence of iron deficiency. This examination estimates the numeral of soluble transferrin receptors within the blood, to enable notice and estimate of iron deficiency and support in the treatment of iron deficiency anemia.

Iron is a necessary nutrient collected from the diet. Transferrin is the primary protein in the blood that affixes to iron and transports it to tissues and cells. Approximately 80% of iron is carried to the bone marrow, where it is employed for the hemoglobin in red blood cells (RBCs), and the remainder is accumulated in other cells and tissues as ferritin and haemosiderin.

How is the specimen compiled for analysis?

A blood specimen is taken by injecting a syringe into a vein in the arm.

Practice is required to ensure the quality of the specimen

As per No examination, preparation is required.

When is it called for?

The soluble transferrin receptor blood examination is not for a regular checkup but may be demanded along with or in follow-up to additional iron examinations when an individual has signs of anemia which are as follow:

• Weakness, exhaustion
• Absence of energy
• Yellowish coloration

This examination may also be mandated when a complete blood count (FBC) indicates decreased levels of hemoglobin and small red blood cells (low MCV).

It may be required when an individual has a normal or near-normal iron level.

Examination outcomes

The gathering of soluble transferrin receptors (sTfR) will be boosted with iron depletion. If the sTfR concentration is raised in individuals with anemia, then the individual may have iron deficiency anemia. If the outcome is within the normal span, then it is more probable that the individual's anemia is due to another reason, for example, chronic disorder or inflammation.